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PM · Lens · Endoplasmic reticulum stress‑induced apoptotic pathway and mitochondrial dysregulation in HeLa cells treated with dichloromethane extract of Dillenia suffruticosa

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Article · Volume 12, Issue 45S · pp. S86–S95

Endoplasmic reticulum stress‑induced apoptotic pathway and mitochondrial dysregulation in HeLa cells treated with dichloromethane extract of Dillenia suffruticosa

Wan Abd Ghani Wan Nor Hafiza2,3, Latifah Saiful Yazan2,4, Yin Sim Tor4, Jhi Biau Foo4, Nurdin Armania2,4, Heshu Sulaiman Rahman5,6

  1. 1Department of Biomedical Sciences, Faculty of Medicine and Health Science, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
  2. 2College of Medical Laboratory Technology, Institute for Medical Research, Jin Pahang, 50588 Kuala Lumpur, Malaysia.
  3. 3Laboratory of Molecular Biomedicine, Institute of Bioscience, Malaysia.
  4. 4Department of Microbiology and Pathology, Faculty of Veterinary Medicine, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
  5. 5UPM-MAKNA Cancer Research Laboratory, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.

Abstract

Keywords: Apoptosis; cell cycle arrest; cervical cancer; Dillenia suffruticosa; endoplasmic reticulum stress

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