Exogenous Intervention with Sodium Hydrosulfite Enhances the Quality of Radix Scutellariae by Modulating Antioxidases and Secondary Metabolites

Abstract

Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored.Objective: To evaluate the antioxidant and anti-inflammatory activities of <em>Cissus arnottiana</em>.Materials and Methods: The antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide, and hydroxyl radical scavenging assays. The anti-inflammatory activity was evaluated using the protein denaturation inhibition assay.Results: The methanolic extract of <em>C. arnottiana</em> showed significant antioxidant activity in all the tested models. The extract also showed significant anti-inflammatory activity by inhibiting protein denaturation.Conclusion: <em>C. arnottiana</em> possesses significant antioxidant and anti-inflammatory activities, which could be attributed to the presence of phytochemicals such as flavonoids and phenolic compounds.

Keywords: Antioxidases; flavonoids; Radix Scutellariae; reactive oxygen species; sodium hydrosulfite