Article · Volume 15, Issue 62S · pp. S155–S161
Physicochemical Standardization of Mucilage Obtained from Althaea officinalis Linn – Root
Mazhar Husain1, Abdul Wadud1, Hamiduddin Hamiduddin2, Gulamuddin Sofi1, Shaista Perveen1, Khadeeja Abdul Hafeez1
- 1Departments of Ilmul Advia (Pharmacology), Institute of Unani Medicine, Bengaluru, Karnataka, India.
- 2Ilmul Saidla (Unani Pharmacy), National Institute of Unani Medicine, Bengaluru, Karnataka, India.
Abstract
Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored.Objective: To evaluate the antioxidant and anti-inflammatory activities of <em>Cissus arnottiana</em>.Materials and Methods: The methanolic extract of <em>C. arnottiana</em> leaves was evaluated for antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide, and hydroxyl radical scavenging assays. Anti-inflammatory activity was assessed using the carrageenan-induced rat paw edema model.Results: The extract showed significant antioxidant activity in a dose-dependent manner. In the anti-inflammatory assay, the extract at 200 and 400 mg/kg doses significantly reduced paw edema compared to the control group.Conclusion: <em>C. arnottiana</em> possesses significant antioxidant and anti-inflammatory properties, supporting its traditional use.
Keywords: Althaea officinalis; mucilage; physicochemical characterization; root; Unani medicine
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