Article · Volume 16, Issue 71 · pp. 670–674
Content Determination and Anti-fatigue Effect of the Purified Anthocyanin from Purple Daucus carota
Fang-Rong Cheng1, Yue-Yue Mao1, Song-Heng Jin2, Rong-Rong Cai2, Ke Yuan2
- 1College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, China.
- 2Jiyang College of Zhejiang Agriculture and Forestry University, Zhu’ji, P.R, China.
Abstract
Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant used in traditional medicine for bone healing.Objective: The present study was aimed to evaluate the anti-inflammatory and analgesic activities of the methanolic extract of <em>Cissus quadrangularis</em> (MECQ) in experimental animal models.Materials and Methods: The anti-inflammatory activity was evaluated using carrageenan-induced rat paw edema model, and analgesic activity was evaluated using acetic acid-induced writhing and tail-flick models in mice.Results: MECQ at doses of 200 and 400 mg/kg showed significant (P < 0.01) anti-inflammatory activity in carrageenan-induced rat paw edema. In analgesic models, MECQ showed significant (P < 0.01) reduction in the number of writhes in acetic acid-induced writhing model and increased the reaction time in tail-flick model.Conclusion: The results suggest that MECQ possesses significant anti-inflammatory and analgesic activities, which supports its traditional use.
Keywords: Anthocyanin; anti-fatigue effect; cyanidin‑3‑o‑glucoside; high performance liquid chromatography; purple Daucus carota
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