Article · Volume 18, Issue 80 · pp. 886–892
Prospecting Indian Barleria Species for their Antioxidants, Anti‑Bronchial, and Anti‑Cancer Compounds
Sandeep R. Pai1, Parthraj R. Kshirsagar2, Nilesh V. Pawar3, Mansingraj S. Nimbalkar4
- 1Department of Botany, Rayat Shikshan Sanstha’s Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, College, Shivaji Peth, Kolhapur, Maharashtra, India.
- 2Department of Botany, Shri Shivaji Mahavidyalaya, Barshi, Maharashtra, College, Shivaji Peth, Kolhapur, Maharashtra, India.
- 3Department of Botany, The New College, Shivaji Peth, Kolhapur, Maharashtra, India.
- 4Laboratory of Cytogenetics and Plant Breeding, Department of Botany, Shivaji University, Vidya Nagar, Kolhapur, Maharashtra, India.
Abstract
Aim: The study herein was performed in view of prospecting 15 species and one variety of Barleria in comparison to Adathoda vasica for phytochemical composition, and antioxidant activities.Materials and Methods: In addition to this, the study also quantifies two anti‑bronchial (vasicine, vasicinone) and one anti‑cancer (betulin) compounds using reversed‑phase high‑performance liquid chromatography analysis.Results: Samples showed betulin ranging from 7.700 to 73.447 mg/g, vasicine from 0.092 to 3.710 mg/g, and vasicinone from 0.005 to 2.752 mg/g. Principal component analysis and hierarchical cluster analysis results signified the division of seventeen samples tested, into two major clades (based on a similarity range 57.83–96.60%).Conclusion: Both phytochemical analysis and antioxidant activities showed variation in the samples tested. Barleria grandiflora had higher content and better activities among the species.
Keywords: Antioxidant activity; Barleria; betulin; total polyphenols; vasicine; vasicinone
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