Article · Volume 2, Issue 6 · pp. 126–127
In vitro anthelmintic activity of Trachyspermum ammi seeds
Abdul Jabbar1, Zafar Iqbal1, Muhammad Nisar Khan1
- 1Chemotherapy Laboratory, Department of Veterinary Parasitology, University of Agriculture, Faisalabad–38040, Pakistan.
Abstract
Development of anthelmintic resistance against commonly used anthelmintics in gastrointestinal nematodes of small ruminants has awakened interest in the study of medicinal plants as alternative sources of anthelmintics. The present study was carried out to evaluate the ovicidal efficacy of Trachyspermum ammi seeds, used locally as anthelmintic for worm control in sheep. Egg hatch test (EHT) was conducted on Haemonchus contortus ova to investigate the in vitro ovicidal effect of crude aqueous (CAE) and methnolic extracts (CME). Lethal concentration 50 (LC50) values of CAE and CME of T. ammi seeds were 0.1698 and 0.1828 mg/ml, respectively. This present study suggests further large scale pharmacological and toxicological studies for its safer use in veterinary medicine.
Keywords: Trachyspermum ammi; Anthelmintic; Haemonchus contortus; Egg hatch test
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