jrnls.org logo
Submit

BROWSE ALL JOURNALS

Type 2 letters to search all 19 journals

SEE ALL 19 JOURNALS
Pharmacognosy MagazineNOW IN
Back

PM · Lens · Studies on diuretic and laxative activity of ethanolic extract and its fractions of Cleome rutidosperma aerial parts

PDF

Article · Volume 2, Issue 7 · pp. 178–179

Studies on diuretic and laxative activity of ethanolic extract and its fractions of Cleome rutidosperma aerial parts

A. A.1, S. S.2, J.K. J.K.3, G.K. G.K.3, T. T.3, S. S.3

  1. 1Institute of Pharmacy and Technology, Salipur, Cuttack – 754 202, Orissa, India.
  2. 2Department of Pharmaceutical Technology, Jadavpur University, Kolkata – 700 032, India.
  3. 3School of Pharmaceutical Sciences, Institute for Technical Education and Research, Bhubaneswar, Orissa-751030, India.

Abstract

Crude ethanolic extract and fractions of Cleome rutidosperma (family: Capparidaceae) was investigated for diuretic and laxative activity in albino rats that was compared with standard drugs Furosemide (10mg/kg, p.o.) and Agar agar (300mg/kg, p.o.), respectively. The extract was found to produce significant diuretic as well as laxative activity in dose dependant manner. Fractions of the extract potentiated the observed activities. The activities may be contributed to the phytoconstituents present.

Keywords: Cleome rutidosperma; Acute toxicity study; Diuretic activity; Laxative activity

The full text of this article is available as a PDF. Open the PDF.