Article · Volume 2, Issue 8 · pp. 239–240
Anti-inflammatory activity of Plumbago capensis
A.I. Charles Dorni1, K.S. Vidyalakshmi1, Hannah R. Vasanthi1, G.V Rajamanickam1, G.P Dubey1
- 1Centre for Advanced Research in Indian System of Medicine (CARISM), SASTRA Deemed University, Thanjavur, Tamil Nadu, India.
Abstract
The HAEPC (Hydroalcoholic extract of Plumbago capensis) showed a maximum of 46.88% inhibitory action on Carrageenan induced paw edema at the dose of 250 mg/kg and inhibited the leukocyte migration in a dose dependent manner. The anti-inflammatory activity observed was comparable to the standard non-steroidal anti-inflammatory drug indomethacin (10mg/kg). Plumbago capensis, a lesser known Plumbago species has significant anti-inflammatory activity with potential constituents targeting different components of inflammatory process.
Keywords: Plumbago capensis; Plumbagin; Peritonitis; HPTLC; Prostaglandin; Carrageenan
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