Article · Volume 2, Issue 8 · pp. 258–260
Evaluation of Anti-inflammatory activity of Nyctanthes arbor-tristis and Onosma echioides.
Amrite Omkar1, Thurackal Jeeja1, Gadgoli Chhaya1
- 1Department of Pharmacognosy, Saraswati Vidya Bhavan’s College of Pharmacy, Dombivli – 421203, Maharashtra, India.
Abstract
Anti-inflammatory activity of the ethanolic extract of the orange tubular calyx of N.arbor-tristis and pet.ether extract of root bark of O.echioides was studied in albino rats of Wistar strain using the carrageenan induced paw edema model. The ethanolic extract of N.arbor-tristis (200 mg/kg, i.p.), isolated carotenoid from the extract N.arbor-tristis (200mg/Kg, i.p.) and pet.ether extract of O.echioides (5mg/Kg, i.p.) inhibited carrageenan induced rat paw edema. The results indicated that all the extract produced significant (p < 0.05) anti-inflammatory activity when compared with the standard drug (diclofenac sodium) and untreated control.
Keywords: Anti-inflammatory; Nycthanthes arbor-tristis; carotenoid; Onosma echioides
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