Research Advancements in Pharmacological Activities and Mechanisms of Matrine

Abstract

Matrine possesses a broad spectrum of pharmacological activities as one of the primary components of Chinese herbal medicine Sophora flavescens extract, along with fewer side effects and low toxicity. Matrine possesses anti-inflammatory, anti-cancer, anti-virus, antibiosis, and anti-oxidative properties and protects the central nervous and cardiovascular systems, immunosuppression, intestinal flora balance regulation, and broad-spectrum insecticidal activities. We reviewed the recent progress in matrine research in terms of the pharmacological activities and associated mechanisms to provide a reference for the wide and safe application of matrine.

Keywords: Matrine; molecular structure; pharmacological activity; mechanism action