Article · Volume 4, Issue 13 · pp. 42–43

n vitro Antioxidant and free radical scavenging potential of Parkinsonia aculeata Linn.

Mruthunjaya K.¹, V.I. V.I.²

¹Department of Pharmacognosy and Phytochemistry, J.S.S. College of Pharmacy, S.S.Nagar, Mysore-570 015, Karnataka, India.
²Herbals Research Division, Dr.Nargund Research Foundation, Dattatreya Nagar, BSK III Stage, 100 feet Ring Road, Bangalore – 560 085, India.

Abstract

Parkinsonia aculeata is found most exclusively in the drier regions of India. Leaves from this plant contain orientin, iso-orientin, vitexin, iso-vitexin, lucenin-II, vicenin-II, diosmetin 6-C-B-glucoside, apigenin, luteolin, kaempferol, chrysoeriol, epi-orientin, parkinsonin-A, parkinsonin-B, and parkintin. In folk medicine, the plant leaves are used to treat jaundice. Due to the presence of flavonoids and its widespread use to treat jaundice, our aim with this study was to evaluate the antioxidant properties of P. aculeata. The antioxidant activity of the 70% hydroalcoholic extract of Parkinsonia aculeata was evaluated in vitro by various experimental parameters such as DPPH radical scavenging activity, nitric oxide scavenging, β-carotene-linoleic acid module system, hydroxyl radical scavenging activity, and lipid peroxidation. Also, ferric ion reduction capability of the evaluated extracts, total antioxidant capacity, and total phenolic content, were also determined. Our results showed that Parkinsonia aculeate displayed potent antioxidant properties, supporting the ethnomedical use given to this plant to treat jaundice.

Keywords: Antioxidant; DPPH; Free radical scavenging; Hydroxyl radical scavenging; Parkinsonia aculeata

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