Article · Volume 4, Issue 14 · pp. 102–103
Influence of cultivation on the chemical composition and antimicrobial activity of Sideritis spp.
Emanuela Kostadinova1, Kalina Alipieva2, Marina Stefova3, Daniela Antonova4, Ljuba Evstatieva5, Gjoshe Stefkov5, Iva Tsvetkova5, Hristo Naydenski5, Vassya Bankova5
- 1Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev str., bl.9, 1113 Sofia, Bulgaria.
- 2Institute of Chemistry, Faculty of Science, P. O. Box 162, 1001 Skopje, R. Macedonia.
- 3Institute of Botany, Bulgarian Academy of Sciences, Sofia, Bulgaria.
- 4Institute of Pharmacognosy, Faculty of Pharmacy, Vodnjanska 17, 1000 Skopje, R. Macedonia.
- 5Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Abstract
Hexane extracts of wild Sideritis scardica Griesb. and of cultivated hybrid S. scardica x S. syriaca were analyzed by GC-MS and tested for antimicrobial activity. Main components of all the extracts were diterpenes and n-alkanes. Cultivated and wild plant extracts demonstrated significant activity against S. aureus. The results demonstrate the possibility to find cultivation conditions that will lead not only to preservation but to increasing of the quantity of biologically active constituents in S. scardica and the biological activity of the extracts.
Keywords: Sideritis; cultivation; diterpenes; antibacterial activity
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