Article · Volume 4, Issue 14 · pp. 126–127
Evaluation of aqueous and methanol extracts of Pistacia integerrima galls as potential immunomodulator.
Uttara P. Joshi1, S. H. Mishra1
- 1Pharmacy Department, Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Vadodara- 390001, India.
Abstract
The aqueous and methanol extracts of Pistacia integerrima (Anacardiaceaea) leaf-galls were evaluated for immunomodulatory and adaptogenic activities using E. coli induced abdominal sepsis, cyclophosphamide induced myelosuppression, carbon clearance test in mice and forced swim test in rats. Both the extracts showed the presence of phenolics, flavonoids, carbohydrates and volatile oils in preliminary phytochemical screening. The Co-TLC of extracts confirmed presence of Gallic acid, and Quercetine known to possess antioxidant activity. The immunomodulatory and adaptogenic activity of above extracts may be attributed to the presence of Gallic acid and Quercetine.
Keywords: Pistacia; phagocytocis; immunomodulation; cyclophosphamide
The full text of this article is available as a PDF. Open the PDF.