jrnls.org logo
Submit

BROWSE ALL JOURNALS

Type 2 letters to search all 19 journals

SEE ALL 19 JOURNALS
Pharmacognosy MagazineNOW IN
Back

PM · Lens · Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes.

PDF

Article · Volume 4, Issue 15 · pp. 207–209

Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes.

P Chattopadhyay1, A.K. Wahi2, N Verma2, A Verma2, V.D. Aher2

  1. 1Microbiology and Cell Biology Laboratory, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
  2. 2Division of Pharmacognosy and PhytoChemistry, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.

Abstract

Nitric oxide (NO) is generated in many mammalian tissues and is an important mediator of both physiological and pathological responses. The present study investigated the effect of alcoholic and aqueous extracts of whole plant of Phyllanthus fraternus Linn in NO production and platelets aggregation. Splenocytes were separated and NO production was measured. Both alcoholic and aqueous extracts showed significant increase in NO production and inhibition of platelets aggregation in chicken lymphocytes at a dose of 600 µg/ ml. The study reveals that P. fraternus may be used in asthma or in cardiovascular implications.

Keywords: Nitric Oxide (NO); Platelets aggregation; Chiken lymphocytes

The full text of this article is available as a PDF. Open the PDF.