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PM · Lens · Taxane Ditepenoids from the Needles of Taxus baccata L. Growing in Iran

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Article · Volume 5, Issue 17 · pp. 67–70

Taxane Ditepenoids from the Needles of Taxus baccata L. Growing in Iran

Mohammad reza Verdian-Rizi1, Abbas Hadjiakhoondi1, Morteza Pirali-Hamedani2, Nargess Yasa1, Golamreza Amin1, Mahnaz Khanavi1

  1. 1Department of Pharmacognosy and Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical sciences, Tehran, Iran.
  2. 2Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Abstract

Chemical examination of the needles and young stems of Taxus baccata L. from Iran, resulted in the isolation of three taxane diterpenoids , two previously reported taxoids, taxupinanane L and taxupinanane G, and a new taxoid, 2,9-deacetyltaxinine J. The structures of these compounds were determined on the basis of spectroscopic data. These three taxoids were not previously encountered in Taxus baccata L. species.

Keywords: Taxus baccata L; isolation; taxoids; Taxaceae

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