Article · Volume 5, Issue 19S · pp. 51–54
Antidiabetic Activity of Aqueous Extract of Eucalyptus citriodora Hook. in Alloxan Induced Diabetic Rats
Arjun Arjun1, Shivesh Shivesh2, Alakh N N3
- 1College of Pharmacy, IFTM, Moradabad – 244 001, U.P, India.
- 2Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra – 835 215, Ranchi, Jharkhand, India.
- 3Department of Pharmaceutics, IT, BHU, Varanasi, India.
Abstract
The present study was undertaken to study the antidiabetic activity of the aqueous extract of Eucalyptus citriodora Hook. leaf in alloxan-induced diabetic rats. The activity of the extract was studied on glucose loaded and alloxan-induced diabetic rats. In both the tests, the extract has shown significant and considerable antidiabetic effect in a dose dependent manner. On oral administration of the extract at a dose of 500 mg/kg of body weight, the reduction of blood glucose level was 22.9% after 4th hr and on continuous administration the reduction in blood glucose level after 21 days was 49.9 and 56.8% with dose of 250 and 500 mg/kg of body weight respectively. Aqueous extract of leaves of E. citriodora exhibited significant antidiabetic activity which was comparable with the standard drug Glibenclamide.
Keywords: Eucalyptus citriodora; antidiabetic; flavonoids; glibenclamide; tannins
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