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Pharmacognosy ResearchNOW IN
Article

GC-MS analysis of bio-active compounds in methanolic extract of Lactuca runcinata DC

1★, 4, 2, 3★ Corresponding author

  1. 1Departments of Pharmacology
  2. 2Pharmaceutical Chemistry
  3. 3Biotechnology, Koringa College of Pharmacy, Tallarevu Mandal, Andhra Pradesh
  4. 4Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India

CORRESPONDENCE

Lakshmi Kanta Kanthal

*Address for correspondence: Asso. Prof. Lakshmi Kanta Kanthal, Department of Pharmacology,Koringa College of Pharmacy, Korangi - 533 461,Tallarevu Mandal, Andhra Pradesh, India.

lkkhaldia@gmail.com

Revised: 25-04-2013.

Volume 6, Issue 1 · pp. 58–61 · 2014 · DOI: 10.4103/0974-8490.122919

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ABSTRACT

Background: The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC.

Objective: The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata.

Materials and Methods: Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientific Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II.

Results: The phytochemical tests showed the presence of alkaloids, cardiac glycosides, flavonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identified representing 84.49% of total methanolic extract composition.

Conclusion: From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.

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    Kanthal, L. K., Dey, A., Satyavathi, K., & Bhojaraju, P. (2014). GC-MS analysis of bio-active compounds in methanolic extract of Lactuca runcinata DC. Pharmacognosy Research, 6(1), 58–61. https://doi.org/10.4103/0974-8490.122919