Article · Volume 6, Issue 1 · pp. 58–61

GC-MS analysis of bio-active compounds in methanolic extract of Lactuca runcinata DC

Lakshmi Kanta Kanthal¹, Akalanka Dey⁴, K. Satyavathi², P. Bhojaraju³

¹Departments of Pharmacology
²Pharmaceutical Chemistry
³Biotechnology, Koringa College of Pharmacy, Tallarevu Mandal, Andhra Pradesh
⁴Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India

Abstract

Background: The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC.

Objective: The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata.

Materials and Methods: Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientific Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II.

Results: The phytochemical tests showed the presence of alkaloids, cardiac glycosides, flavonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identified representing 84.49% of total methanolic extract composition.

Conclusion: From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.

Keywords: GC-MS analysis; Lactuca runcinata; phytochemical screening; whole plant methanol extract

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