Volumes & Issues

Elahe Aleebrahim-Dehkordy, Sadra Ansaripour, Mahmoud Rafieian-Kopaei, Shirin Saberianpour

pp. 1–6 · DOI: 10.4103/phrev.phrev_48_17 · 2018

The roles of thyroid glands in different functions of the body have been well explained such that hypothyroidism and hyperthyroidism can impair the metabolism and normal functions of the body’s tissues. Recently, using m…

Prasanna Habbu, Mahesh Hiremath, Smita Madagundi, Rashmi Vankudri, Basavraj Patil, Chetan Savant

pp. 7–19 · DOI: 10.4103/phrev.phrev_33_17` · 2018

Phytopharmaceuticals stand out as recent promising candidates for the treatment of chronic diseases. Nanotechnology has become an important part of pharmaceutical industry, since it involves the development of novel drug…

Islamudin Ahmad, Arry Yanuar, Kamarza Mulia, Abdul Mun’im

pp. 20–26 · DOI: 10.4103/phrev.phrev_40_17 · 2018

Background: Ionic liquid‑based microwave‑assisted extraction (IL‑MAE) is one of the non-conventional extraction methods that has been developed and applied in recent years. Some studies have reported the success of this …

Fatemeh Heydarpour, Masoomeh Abasabadi, Zahra Shahpiri, Siavash Vaziri, Hesam Aldin Nazari, Fariba Najafi, Maryam Mirzaei, Mohammad Hosein Farzaei

pp. 27–39 · DOI: 10.4103/phrev.phrev_37_17 · 2018

Considering the unclear etiology of recurrent aphthous ulcers (RAUs), the clinical management of RAU is based on no optimal therapeutic approach. The current study aimed to review the clinical trials on the effectiveness…

Agustina Dwi Retno Nurcahyanti, Zita Arieselia, Sandy Vitria Kurniawan, Fitmawati Sofyan, Michael Wink

pp. 40–45 · DOI: 10.4103/phrev.phrev_20_17 · 2018

Worldwide, the diabetes epidemic is rapidly increasing and has become a growing health threat over the past few decades. The continuous investigation into the development of antidiabetic agents and treatments is crucial …

Dominic Augustine, Roopa S. Rao, Jayaraman Anbu, K. N. Chidambara Murthy

pp. 46–55 · DOI: 10.4103/phrev.phrev_45_17 · 2018

In recent times, naturally occurring substances such as earthworm extracts have been used successfully as an antimicrobial and anti‑inflammatory agent in wound healing. It has also shown promising antitumor activity in c…

Rahul Raghavan, Sanith Cheriyamundath, Joseph Madassery

pp. 56–65 · DOI: 10.4103/phrev.phrev_47_17 · 2018

This review explores the mechanisms of cytotoxic and anti‑inflammatory properties of andrographolide and derivatives of andrographolide in various cell lines. In vitro and in vivo studies that shed light on the molecular…

Vishwas Tripathi, Anjana Singh, Mohd. Tashfeen Ashraf

pp. 66–71 · DOI: 10.4103/phrev.phrev_34_17 · 2018

Avenanthramides (Avns) are polyphenols found exclusively in oats. Consumption of oats has been linked with a decreased risk of several important diseases such as cancer, diabetes and cardiovascular diseases. Avns possess…

Charu Khanna, Shalini Singh, Manish Vyas

pp. 72–77 · DOI: shalinisingh.iit@gmail.com · 2018

One of the most interesting areas in scientific research has been drug discovery. The discovery of antibiotics led to the improvement of the overall health status of the general population, but in the present scenario, i…

Francisca Idalina Neta, Ianara Mendonça Da Costa, Francisca Overlânia Vieira Lima, Luciana Cristina Borges Fernandes, José Rodolfo Lopes De Paiva Cavalcanti, Marco Aurélio De Moura Freire, Eudes Euler De Souza Lucena, Amália Cinthia Meneses Do Rêgo, Irami Araújo Filho, Eduardo Pereira De Azevedo, Fausto Pierdoná Guzen

pp. 78–84 · DOI: 10.4103/phrev.phrev_46_17 · 2018

Introduction:Mucuna pruriens (L.)DC. (Mp) has been used in the treatment of numerous diseases in Indian Ayurvedic medicine, mainly for delaying the symptoms of Parkinson’s disease (PD), and has as its main component levo…

João Paulo Bastos Silva, Suellen Carolina Martins do Nascimento, Daniele Hidemi Okabe, Ana Carla Godinho Pinto, Fábio Rodrigues de Oliveira, Thiago Portal da Paixão, Maria Lúcia Souza Siqueira, Ana Cristina Baetas, Marcieni Ataíde de Andrade

pp. 85–93 · DOI: 10.4103/phrev.phrev_50_17 · 2018

Petiveria alliacea is a perennial Amazonian shrub used in traditional medicine for many purposes worldwide, including as antirheumatic, antispasmodic, antifungal, and analgesic for pain relief. Herein, this review aimed …

Martha Ervina, Sukardiman S

pp. 94–102 · DOI: 10.4103/phrev.phrev_41_17 · 2018

Chinaberry (Melia azedarach L., Meliaceae), a Mahogany family usually used as high quality timber, is native to Asia but now is found in other parts of tropical world continent. The leaves, fruits, bark, seed and root ar…

Ali Hafez El‑Far, Hazem M. Shaheen, Abdel Wahab Alsenosy, Yasser S. El‑Sayed, Soad K. Al Jaouni, Shaker A. Mousa

pp. 120–127 · DOI: 10.4103/phrev.phrev_29_17 · 2018

Medicinal plants are sources of novel drug discovery targets. Costus speciosus is an important medicinal plant widely used for the treatment of various ailments. The plant has multiple active ingredients and has been fou…

Mina Cheraghi Niroumand, Fatemeh Heydarpour, Mohammad Hosein Farzaei

pp. 103–114 · DOI: 10.4103/phrev.phrev_22_17 · 2018

Vitex agnus‑castus L., known as the chaste tree, is a small deciduous tree which its fruits have been used for more than 2500 years in ancient Egypt, Greece, Iran, and Rome for a variety of gynecologic problems. It has a…

Parsa Ravanfar, Golnaz Namazi, Afshin Borhani-Haghighi, Shaghayegh Zafarmand

pp. 115–119 · DOI: 10.4103/phrev.phrev_28_17 · 2018

Licorice (Glycyrrhiza glabra) is an herbal medicine with several pharmacologic properties in ancient traditional medicine. Studies have provided evidence on its clinical efficacy in variety of medical conditions. There a…

Oluwakemi Adetutu Bello, Opeyemi Isaac Ayanda, Oluwadurotimi Samuel Aworunse, Babafemi Ibukun Olukanmi, Michael Olasunkanmi Soladoye, Edward Babatunde Esan, Olawole Odun Obembe

pp. 128–132 · DOI: 10.4103/phrev.phrev_43_17 · 2018

Solanecio biafrae (Olive and Hierne) C. Jeffrey (1986) (Family: Asteraceae), has synonyms Senecio biafrae Olive and Hierne (1877) and Crassocephalum biafrae (Olive and Hierne) S. Moore (1912). It is a perennial standent,…

Mengome Line Edwige, Mewono Ludovic, Aboughe-Angone Sophie

pp. 133–137 · DOI: 10.4103/phrev.phrev_42_17 · 2018

Loa loa filarial worm affects humans living in rural areas, urban slums, or conflict zones. This parasite is responsible for neglected tropical diseases, endemic in rainforest areas of the West and Central African. L. lo…