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Review

A Systematic Review on the Antibacterial Activity of Punica granatum L. against E. coli

Jeen Hernandez Magbuhat1★, Paulene Dinglasan Bool1, Kristine Jane Rios Olit1, Diana Rose Olavidez Sales1, Axel An Lee Mangalonzo1, Franzyn Evol Uy Montances1, Sophia Galang Gallardo1, Gilmar Chrys Parreño Salenga1, Carl Vincent Del Rosario Arizala1★ Corresponding author

  1. 1Department of Medical Technology, Institute of Arts and Sciences, Far Eastern University Manila, PHILIPPINES.

CORRESPONDENCE

Jeen Hernandez Magbuhat

Department of Medical Technology, Institute of Arts and Sciences, Far Eastern University Manila, PHILIPPINES.

jeen.magbuhat@gmail.com

Received: 23-08-2022; Revised: 14-09-2022; Accepted: 02-11-2022.

Volume 11, Issue 3 · pp. 631–639 · PUBLISHED · DOI: 10.5530/ajbls.2022.11.84

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ABSTRACT

Background: The global crisis in shortage production and overuse of antibiotics resulted in the resurfacing of drug-resistant bacteria, posing a threat to the effects of conventional antibiotics. The medicinal plant Punica granatum L. (pomegranate) has been widely studied for its antimicrobial effects against bacteria, fungi, and helminths, because of the phytochemicals present in the different parts of the plant (leaves, petals, peels, seeds, and fruit). Studies show that pomegranate is effective against the potent gram-negative bacterium, Escherichia coli (E. coli). Different strains of E. coli are highly drug-resistant and multidrug-resistant. Hence, the objective of this paper is to determine the antibacterial efficacy of phytochemicals found in the different parts of pomegranate against E. coli. Materials and Methods: To review the antibacterial activity ofPunica granatum L. against E. coli, online databases such as PubMed, and ScienceDirect were used to search for journals and studies published between 2013-present. Search terms include “Pomegranate”, “Punica granatumL.”, “Antibacterial”, “E. coli”, and “Extract”. And software named Zotero was used for the removal of duplicates. Conclusion:After the analysis, this review reveals that polyphenols, specifically flavonoids, and tannins, are the most common class of compounds present in many parts of pomegranate including the leaf, peel, and exocarp that exert antibacterial properties against E. coli.

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    Magbuhat, J. H., Bool, P. D., Olit, K. J. R., Sales, D. R. O., Mangalonzo, A. A. L., Montances, F. E. U., Gallardo, S. G., Salenga, G. C. P., & Arizala, C. V. D. R. (). A Systematic Review on the Antibacterial Activity of Punica granatum L. against E. coli. Asian Journal of Biological and Life sciences, 11(3), 631–639. https://doi.org/10.5530/ajbls.2022.11.84