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Asian Journal of Biological and Life sciencesNOW IN
Article

Green Synthesis of AgNP Using Ficus benghalensis Aerial Root and its AchE Inhibiting Property

Chelladurai Iyyanar MD (S)1★, Ayyanar Pandurangan2, Shanmugapriya Narayanan3, K. Santhi4, H.M. Nilofer Nisha5★ Corresponding author

  1. 1Department and Library, Siddha Central Research Institute, Central Council for Research in Siddha (Ministry of Ayush, Govt of India), Anna Govt. Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.
  2. 2Department of Biochemistry, Siddha Central Research Institute, Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.
  3. 3Department of Microbiology, Shrimati Indira Gandhi College, Tiruchirappalli, Tamil Nadu, INDIA.
  4. 4Department of Botany, Selvamm Arts and Science College (Autonomous), Namakkal, Tamil Nadu, INDIA.
  5. 5Department of Microbiology, Helikem Biotek Industrial Research Pvt, Ltd., Tiruchirappalli, Tamil Nadu, INDIA.

CORRESPONDENCE

Chelladurai Iyyanar MD (S)

Department and Library, Siddha Central Research Institute, Central Council for Research in Siddha (Ministry of Ayush, Govt of India), Anna Govt. Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.

panduayyanar@gmail.com

Received: 22-06-2023; Revised: 15-07-2023; Accepted: 16-09-2023.

Volume 12, Issue 2 · pp. 415–421 · PUBLISHED · DOI: 10.5530/ajbls.2023.12.55

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ABSTRACT

Aim:The aim of the study was to analyze the phytochemical components of adventitious roots of Ficus benghalensis and its biopotential ability on silver nanoparticle reduction.Materials and Methods:Aerial root was collected and its phytochemical was extracted with acetone and phytochemical detected by GCMS. AgNP is characterized by UV and SEM analysis. DPPPH antioxidant, and AchE inhibition were performed.Results:GCMS reveals 20 different peaks 19 different compounds predominantly with 2-Lauro-1,3-Didecoin, Alpha. Tocospiro A and 2h-1,2,3- Triazole-4-Carboxylic Acid, 2-(2-Fluorophenyl). The extract reduced silver at a 1:9 ratio and the time frame were recorded by 5 min to produce nanoparticles. The UV-vis adsorption spectra show the absorbance peak in the range of 430 nm and SEM reveals size of AgNP was 62 nm rectangle shapes. The free radical scavenging activity of hydroalcoholic extract ofF. benghalensisroot was determined and found to be more effective antioxidant activity than standard. AchE inhibition was moderate on root extract and significantly inhibited by AgNP.Conclusion: Green silver nanoparticle reduced by aerial root and its antioxidant potential along with inhibition of Acetylcholine esterase is still considered the main therapeutic strategy against Alzheimer’s Disease. The study plantF. benghalensiswill improve cognitive function and were screened for acetylcholinesterase inhibitory activity with nano drug delivery also a better candidate for future disease-modifying therapies against this devastating disease.

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    (S), C. I. M., Pandurangan, A., Narayanan, S., Santhi, K., & Nisha, H. N. (). Green Synthesis of AgNP Using Ficus benghalensis Aerial Root and its AchE Inhibiting Property. Asian Journal of Biological and Life sciences, 12(2), 415–421. https://doi.org/10.5530/ajbls.2023.12.55