Beyond Seizures: Exploring Cannabidiol in Dravet Syndrome

ABSTRACT

Aim: Dravet Syndrome (DS) is a severe epileptic and developmental encephalopathy causing drug-resistant seizures and developmental delay; this report presents two infant cases and evaluates CBD as adjunct therapy. Materials and Methods: Clinical case details, genetic testing (SCN1A) and treatment response were recorded and monitored. Results: Cannabidiol (CBD) added to regimens provided improved seizure control in refractory cases, with noted adverse effects including somnolence and GI upset. Conclusion: CBD may be beneficial for seizure control in DS but requires careful monitoring and further research on pediatric dosing.

KEYWORDS

• Cannabidiol
• Dravet syndrome
• Pediatric patient
• SCN1A Mutation

Showing references and in-text citations exactly as published.

• DOI10.5530/ajbls.2024.13.106Copy

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