jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Asian Journal of Biological and Life sciencesNOW IN
Article

Assessment of Antibiotic Resistance Profile in Uropathogenic E. coli Isolates from Clinically Presumed UTI Patients in Telangana

Suripeddi Ravi Kiran1, Gujjula Rahul2, Jammula Achyutha Devi3★★ Corresponding author

  1. 1Department of Botany and Food and Nutrition, R.B.V.R.R. Women’s College, Narayanaguda, Hyderabad, Telangana, INDIA.
  2. 2Department of Biochemistry, Osmania University, Hyderabad, Telangana, INDIA.
  3. 3Department of Zoology, R.B.V.R.R. Women’s College, Narayanaguda, Hyderabad, Telangana, INDIA.

CORRESPONDENCE

Jammula Achyutha Devi

Department of Zoology, R.B.V.R.R. Women’s College, Narayanaguda, Hyderabad, Telangana, INDIA.

achyuthadevi@gmail.com

Received: 08-12-2025; Revised: 19-02-2026; Accepted: 27-04-2026.

Volume 15, Issue 1 · pp. 70–80 · PUBLISHED 2026 · DOI: 10.5530/ajbls.20260064

View on AJBLS original site ↗

ABSTRACT

Purpose: The purpose of the current investigation is to assess the antibiotic susceptibility pattern of Escherichia coli (E. coli) isolated from urine samples of patients suspected of having UTIs. The majority among them tested positive for E. coli in the culture. Results: The Minimum inhibitory concentration of Trimethoprim/Sulfamethoxazole was highest and that of Ciprofloxacin was the least for E. coli. The isolated samples showed the highest level of resistance towards Ampicillin (22%), followed by Nalidixic Acid (20%), Ciprofloxacin (20%), Cefuroxime (18%), Cefuroxime axetil (18%), and Ceftriaxone (17%). The demographic statistical data show that women prone more to UTIs with a higher incidence at 21-30 years age group. Significant colony growth in different age groups in In-patient samples showing was observed. The β-lactamase-producing E. coli were high in both in-patient and out-patient urine samples. The nitrite test and distribution of pus cells confirmed the presence of UTI in most samples. Further, higher amounts of CTX-M type of Extended-spectrum β-lactamase producing E. coli were observed in urine samples of in-patients that unequivocally show the organism's resistance to different classes of antibiotic drugs. Conclusion: The results indicate that most cases of UTIs were caused in females which were mostly because of the multidrug-resistant E. coli.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Kiran, S. R., Rahul, G., & Devi, J. A. (2026). Assessment of Antibiotic Resistance Profile in Uropathogenic E. coli Isolates from Clinically Presumed UTI Patients in Telangana. Asian Journal of Biological and Life sciences, 15(1), 70–80. https://doi.org/10.5530/ajbls.20260064