jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Asian Journal of Biological and Life sciencesNOW IN
Article

Antimutagenic Activity of Probiotic Bifidobacterium and Lactobacillus spp. by Ames Test

Reza kazemi Darsanaki1★, Morteza Azizollahi Aliabadi2, Mohammad Mohammad Doost Chakoosari2, Abolfazl Amini3, Fatemeh (Elham) Alikhani2★ Corresponding author

  1. 1Young Researchers Club, Lahijan Branch, Islamic Azad University, Lahijan, IRAN.
  2. 2Department of Microbiology, Faculty of Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN.
  3. 3Laboratory Science Research center, Laboratory Sciences Department School of Paramedical, Golestan University of Medical Sciences, Gorgan, IRAN.

CORRESPONDENCE

Reza kazemi Darsanaki

Young Researchers Club, Lahijan Branch, Islamic Azad University, Lahijan, IRAN.

Reza_kazemi_d@yahoo.com

Received: 10-06-2013; Revised: 22-06-2013; Accepted: 06-07-2013.

Volume 2, Issue 2 · pp. 142–145 · PUBLISHED 31 August 2013 · DOI:

View on AJBLS original site ↗

ABSTRACT

Probiotics are live microbial food supplements that are considered to be beneficial for humans and animals. Many researchers have showed that probiotic bacteria can be effective to decrease cancer risk. In this study, Antimutagenic activities of four probiotic Bifidobacterium and Lactobacillus spp. against three potent mutagen acrylic amide, sodium azide and 2-nitrofluorene were examined by Ames test using Salmonella typhimurium TA100. Results showed Bifidobacterium and Lactobacillus spp. can inhibit mutagen agents unit 40%, That is very good antimutagenic activity. Bifidobacterium bifidum PTCC 1644 displayed the highest antimutagenic activity than other bacteria (inhibition 52.22% acrylic amide, 50.80% sodium azide and 48.66%, 2-nitrofluorene). Antimutagenic activity was increased significantly when there were liver microsome extract (S ).

KEYWORDS

    Open in new tab

    REFERENCES

    As published

    Showing references and in-text citations exactly as published.

      Cite this article

      SELECT FORMAT

      Darsanaki, R. K., Aliabadi, M. A., Chakoosari, M. M. D., Amini, A., & Alikhani, F. E. (2013). Antimutagenic Activity of Probiotic Bifidobacterium and Lactobacillus spp. by Ames Test. Asian Journal of Biological and Life sciences, 2(2), 142–145.