jrnls.org logo
Submit

BROWSE ALL JOURNALS

SEE ALL 19 JOURNALS
Asian Journal of Biological and Life sciencesNOW IN
Article

Evaluation of Effects of Aqueous Extract of Ficus capensis (thunb.) leaves in Adult Albino Rats

Justina Ndirika Chikwendu1★, Joy Ugo Nwamarah1, Vivian A. Uchegbu1★ Corresponding author

  1. 1Department of Home Science Nutrition and Dietetics, University of Nigeria, Nsukka, NIGERIA.

CORRESPONDENCE

Justina Ndirika Chikwendu

Department of Home Science Nutrition and Dietetics, University of Nigeria, Nsukka, NIGERIA.

justina.chikwendu@unn.edu.ng

Received: 05-09-2015; Revised: 12-10-2015; Accepted: 12-11-2015.

Volume 4, Issue 3 · pp. 185–188 · PUBLISHED 31 December 2015 · DOI:

View on AJBLS original site ↗

ABSTRACT

The study evaluated the effect of aqueous extract of Ficus capensis leaves in albino rats. The study specifically investigated the effect of the extract on some liver enzymes (aspartate aminotransferase (AST) and alanine aminotransferase (ALT)) activities, the packed cell volume (PCV), total white blood cell count and differential white blood cell count of the rats. Effect of the extract on serum urea and creatinine levels were also studied. Twenty-five (25) adult male albino rats were used for the study. The extract was prepared and the solution was filtered and fed the rats (25%, 50%, 75% and 100%) of the filtrates. Tap water was fed to the control rats. All the parameters were assessed using standard methods. One –way analysis of variance was used to obtain the means from the biochemical result. The means obtained were separated using Duncan Student Multiple Range Test. Results obtained showed that ALT, AST and creatinine levels of the rats that were fed 100% Ficus capensis extract were significantly higher than those that were fed diluted Ficus capensis extract. Hence, this had adverse effects on the liver cells of the rats. Also result showed that there is improved nutritional status and immunity when properly diluted

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Chikwendu, J. N., Nwamarah, J. U., & Uchegbu, V. A. (2015). Evaluation of Effects of Aqueous Extract of Ficus capensis (thunb.) leaves in Adult Albino Rats. Asian Journal of Biological and Life sciences, 4(3), 185–188.