Cytotoxic Effects of Luteolin Isolated from Feronia limonia Linn.
Jayashree Hanchinalmath1, Ramesh Londonkar1, Kirankumar Shivasharanappa2★★ Corresponding author
- 1Department of Biotechnology, Gulbarga University, Gulbarga, Karnataka, INDIA.
- 2Department of Life Sciences, Garden City University, Bengaluru, Karnataka, INDIA.
CORRESPONDENCE
Kirankumar Shivasharanappa
Department of Life Sciences, Garden City University, Bengaluru, Karnataka, INDIA.
Received: 22-09-2020; Revised: 13-11-2020; Accepted: 12-12-2020.
Volume 9, Issue 3 · pp. 302–305 · PUBLISHED 30 December 2020 · DOI: 10.5530/ajbls.2020.9.45
ABSTRACT
Aim:To evaluate cytotoxic properties ofFeronia limoniaLinn. in different test systems.Methods:In the present study, we have evaluated germination of green grams, viability of yeasts and potato disc assay for rapid and inexpensive screening of drugs exhibiting cytotoxic properties of the isolated compound in comparison with the standard drug. Seed germination parameters- rootlet growth and inhibition were assayed. Yeast viability by spectrophotometric and methylene blue staining method.Results:Zone of inhibition study againstAgrobacterium tumefaciensand potato disc assay has shown a distinct interference of plant extracts against tumor formation and bacterial growth, there by its effect is attributing to antitumor and growth inhibitor properties.Conclusion:This screening test helps in identifying the potential plant types that can be used for medicinal purposes against specific microbe and also as a nutritional supplement for fighting against the free oxide radicals.
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Hanchinalmath, J., Londonkar, R., & Shivasharanappa, K. (2020). Cytotoxic Effects of Luteolin Isolated from Feronia limonia Linn.. Asian Journal of Biological and Life sciences, 9(3), 302–305. https://doi.org/10.5530/ajbls.2020.9.45