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Free Radicals and AntioxidantsNOW IN
Article

Antioxidant and antimicrobial activities of Callistemon comboynensis essential oil

Mohamed I. Abdelhady1,2★, Hamdy A. H. Aly3★ Corresponding author

  1. 1Department of Pharmacognosy, Faculty of Pharmacy, Umm Al-Qura University, Makkah, P.O. Box 715, Saudi Arabia.
  2. 2Pharmacognosy Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
  3. 3Environmental Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), Sadat city – Menofia University, Egypt.

CORRESPONDENCE

Mohamed I. Abdelhady

Department of Pharmacognosy, Faculty of Pharmacy, Umm Al-Qura University, Makkah, P.O. Box 715, Saudi Arabia.

mohibrahem@yahoo.com

Volume 2, Issue 1 · pp. 37–41 · PUBLISHED · DOI: 10.5530/ax.2012.2.8

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ABSTRACT

Introduction: The genus Callistemon is known in folk medicine for its anticough, antibronchitis, and insecticidal effects and its volatile oils have been used as antimicrobial and antifungal agents. Methods:The essential oils obtained by hydrodistillation of the leaves of Callistemon comboynensis (Cc) was investigated by GC/MS. Antioxidant activity of Cc was investigated using 1,1-diphenyl-2-picrylhydrazyl (DPPH). The antimicrobial activity of the essential oil of Cc was evaluated against both gram positive (Bacillus subtilis and Staphylococcus aureus), gram negative (Proteus vulgaris, Pseudomonas aeruginosa) and a pathogenic fungus Candida albicans. Results: It was found that Cc afford 0.22% volatile oil. The major components of the volatile oil of Cc are 1, 8-cineol (53.03%), eugenol (12.1%), methyl eugenol (9.2%) and α-pinene (8.3%). The oil had pronounced antibacterial and antifungal activities on all the tested microbes. Nevertheless, Cc leaf oil extract exhibited high antioxidant activity (91.1 ± 0.3 %) at a concentration of 1000 µg.ml-1, comparable to 100 µg.ml-1 gallic acid (95.7 ± 2).

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    Abdelhady, M. I., & Aly, H. A. H. (). Antioxidant and antimicrobial activities of Callistemon comboynensis essential oil. Free Radicals and Antioxidants, 2(1), 37–41. https://doi.org/10.5530/ax.2012.2.8