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Studies on phytochemical and In-Vitro antioxidant potential of Justicia beddomei (Clarke) Bennett

Akash Marathakam1★, Kannappan N2, Jasemine S1, Santhiagu A3, Sreejith M1, Ajith MP4★ Corresponding author

  1. 1Department of Pharmaceutical Chemistry, National College of Pharmacy, Calicut, Kerala, India.
  2. 2Department of Pharmacy, Annamalai University, Annamalai Nagar 608002, Tamil Nadu, India.
  3. 3Department of Biotechnolgy, National Institute of Technolgy, Calicut, Kerala, India.
  4. 4Department of Pharmaceutical Chemistry, National College of Pharmacy, Calicut, Kerala, India.

CORRESPONDENCE

Akash Marathakam

Department of Pharmaceutical Chemistry, National College of Pharmacy, Calicut, Kerala, India.

akashmarathakam@gmail.com

Received: 12-05-2012; Revised: 10-07-2012; Accepted: 04-11-2012.

Volume 2, Issue 4 · pp. 26–31 · PUBLISHED · DOI: 10.5530/ax.2012.4.5

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ABSTRACT

Introduction: The current study was carried out to investigate the phytochemical constituents and in vitro antioxidant potential of the aerial parts of Justicia beddomei (Clarke) Bennett belonging to the family Acanthaceae. The aerial part of J. bebbomei is traditionally used as a hepatoprotective, antitussive and antispasmodic. Methods: The dried powdered aerial parts of J. beddomei were extracted using petroleum ether, chloroform, ethyl acetate and methanol using a soxhlet extractor and preliminary phytochemical screening was performed using standard protocols. All the extracts were evaluated for their potential antioxidant activities using tests such as DPPH, hydroxyl radical, superoxide anion radical scavenging abilities, β-carotene-linoleic acid model, reducing power ability and total phenolic and flavonoid contents. Results: Preliminary screening revealed the presence of bioactive components especially phenolics and flavonoids in all the extracts. The phenolic and flavonoid content was found to be highest in methanolic extract and lowest in petroleum ether extract. All extracts showed strong antioxidant activity when compared with the standard. Conclusion: The results of the present study indicate that the aerial part extracts of J. beddomei is a good source of antioxidant constituents.

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    Marathakam, A., N, K., S, J., A, S., M, S., & MP, A. (). Studies on phytochemical and In-Vitro antioxidant potential of Justicia beddomei (Clarke) Bennett. Free Radicals and Antioxidants, 2(4), 26–31. https://doi.org/10.5530/ax.2012.4.5