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Indian Journal of Pharmacy PracticeNOW IN
Article

Gingival Overgrowth on Chronic use of Amlodipine: A Case Report

Muhammed Rashid Parambil Peedikkal1, Juny Sebastian1★, Madhan Ramesh1, Narayanappa Doddaiah2, Sathya Narayana Prashanth2★ Corresponding author

  1. 1Department of Pharmacy Practice, JSS College of Pharmacy, Jagadguru Shri Shivarathreeshwara University, S S Nagara, Mysuru, INDIA.
  2. 2Department of Paediatrics, JSS Medical College and Hospital, Jagadguru Shri Shivarathreeshwara University, S S Nagara, Mysuru, INDIA.

CORRESPONDENCE

Juny Sebastian

Department of Pharmacy Practice, JSS College of Pharmacy, Jagadguru Shri Shivarathreeshwara University, S S Nagara, Mysuru, INDIA.

junysebastian@jssuni.edu.in

Volume 10, Issue 4 · pp. 298–301 · PUBLISHED · DOI: 10.5530/ijopp.10.4.61

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ABSTRACT

Background:Amlodipine, a calcium channel blocker (CCB) which is a commonly prescribed antihypertensive medication. Nifedipine is the CCB which is most frequently associated with drug induced gingival overgrowth.Case report: A 9 year old girl presented to the out-patient department of the hospital with the complaints of swelling of left side of cheek with mild to moderate grade pain since 5-6 days.The pain increased on touching and during jaw movements. Her past medical history revealed that she was a known case of cardiomyopathy with bilateral renal artery stenosis with hypertension and was on oral medications amlodipine (5 mg BD), furosemide (40 mg BD) and carvedilol (3.125 mg BD) for the past three years. She was diagnosed as having gingival overgrowth induced by the use of amlodipine. The gingival overgrowth was managed with dental extraction, drainage of abscess and gum cartilage following the withdrawal of the offending drug amlodipine. Alternatively she was started on oral prazosin (1 mg BD) along with other regular medications. Conclusion: Though the incidence of amlodipine causing the gingival overgrowth is less when compared to other drugs in the CCB class, the patients have to be monitored for the gingival overgrowth when on chronic use.

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    Peedikkal, M. R. P., Sebastian, J., Ramesh, M., Doddaiah, N., & Prashanth, S. N. (). Gingival Overgrowth on Chronic use of Amlodipine: A Case Report. Indian Journal of Pharmacy Practice, 10(4), 298–301. https://doi.org/10.5530/ijopp.10.4.61