Persistent Invasive Mole: A Case Report
Prathyusha Kusuma1, Bhargavi Neela1, Balasankar Ramavath2★★ Corresponding author
- 1Department of Clinical Pharmacy and Pharm.D, Vaagdevi College of Pharmacy, Hanamkonda, Warangal, Telangana, INDIA.
- 2Department of Oncology, Kakatiya Medical College, Mahatma Gandhi Memorial Hospital, Warangal, Telangana, INDIA.
CORRESPONDENCE
Balasankar Ramavath
Department of Oncology, Kakatiya Medical College, Mahatma Gandhi Memorial Hospital, Warangal, Telangana, INDIA.
Volume 14, Issue 1 · pp. 68–71 · PUBLISHED · DOI: 10.5530/ijopp.14.1.14
ABSTRACT
Gestational trophoblastic disease is a group of interrelated lesions arising from the trophoblastic epithelium of placenta after abnormal fertilization. It is a disease of women with pregnancy related tumors. Invasive mole, a common manifestation of gestational trophoblastic disease is characterized by villi accompanying trophoblastic overgrowths and invasion which penetrate deep into the myometrium sometimes involving peritoneum or vaginal vault. Here we present a case of persistent invasive mole in a patient who underwent dilation and curettage twice with persistent vaginal bleeding and elevated serum β-human Chorionic Gonadotropin levels. Investigations revealed enlarged uterus with adnexal pathology, Histopathological examination of Dilation and Curettage showed presence of villi and trophoblastic tissue, increased serum β-hCG levels. The patient is successfully treated and managed with methotrexate chemotherapy. This study is focused on the significance of follow-up of the patient as there are more chances of recurrence associated with gestational trophoblastic disease.
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Kusuma, P., Neela, B., & Ramavath, B. (). Persistent Invasive Mole: A Case Report. Indian Journal of Pharmacy Practice, 14(1), 68–71. https://doi.org/10.5530/ijopp.14.1.14