A Prospective Study on Drug Prescription Pattern of Chemotherapeutic Agents in Breast Cancer Patients in a Tertiary Care Hospital

ABSTRACT

Background: Breast cancer is a multi-factorial disease, comprises a group of heterogeneous and complex diseases that evolves due to uncontrolled cellular growth, differentiation and the loss of normal programmed cell death. The present study was explicitly aimed to assess the prescription pattern of chemotherapeutic agents in breast cancer patients in a tertiary care hospital. Materials and Methods:The demographic details and required relevant treatment chart information of patients who met the inclusive standards have been entered into specially designed proforma for the evaluation of prescription pattern against standard NCCN guidelines. The study was conducted in December 2020 to May 2021 at medical oncology department, SVIMS, SPMC (W), Tirupati, and Andhra Pradesh. Results: A total of 75 patients were included in this study. The most prescribed combinational regimen had been found to be Adriamycin, Cyclophosphamide and Taxanes (ACT), which were utilised in 29.33% of patients. Trastuzumab was the most prescribed monotherapeutic agent in 10.6% Patients. Apart from Ondansetron, Dexamethasone and Ranitidine which were considered nearly in all the patients, Promethazine and PEG filgrastim have been set up in 53.3% and 44%. Neoadjuvant chemotherapy in 13 patients, adjuvant chemotherapy in 30 patients and chemotherapy alone in 32 Patients were established. Conclusion: The drugs prescribed had been determined to be rational and acknowledged to preclude the development of ailment keeping the compliance with respective NCCN guidelines. Smaller pattern length might be a restricting thing ceasing the in-intensity analysis.

KEYWORDS

• Breast cancer
• Drug prescription pattern
• Neoadjuvant chemotherapy drugs
• Adjuvant chemotherapy drugs

Showing references and in-text citations exactly as published.

• DOI10.5530/ijopp.16.3.33Copy

RELATED ARTICLES

Matched on section and article type within this issue of IJPP.

• Article · VOLUME 16, ISSUE 3The Impact of SIX SIGMA DMAIC Methodology in the Effective Pharmacy Inventory Management System in a Major Trauma Care Center – A Prospective Observational StudyBritto Duraisingh Lourdu, Kumutha Theivasigamani, Anagha Harwin, Kensylin Paulraj, Sandra Paul, Akash Lachmanan · pp. 191–199Original ArticleSame type: Article
• Article · VOLUME 16, ISSUE 3Prevalence and Evaluation of Self-Medication Practices in Butwal, Rupandehi, NepalMukesh Kumar Chaudhary, Krishna Kala Gaire, Pooja Gupta, Sushmita Banjade · pp. 200–205Original ArticleSame type: Article
• Article · VOLUME 16, ISSUE 3Assessment of Students at Pharmacy Colleges in the Kolhapur District of Maharashtra, India, in Terms of their Knowledge, Attitudes, and Practices (KAP) towards Responsible Self-MedicationRitesh D. Vyavahare, Mithun G. Maniyar, Pankaj R. Khuspe, Ramdas S. Naiknaware, Vrunal V More, Anil V. Landage, Sushant S. Dhandore · pp. 213–216Original ArticleSame type: Article
• Article · VOLUME 16, ISSUE 3Evaluation of Antibiotic Utilization in Otitis Media and Otitis Externa in Tertiary Care HospitalSuha Zulekha, Sumithra Devadiga, Zuha Shyma, Sajan Francis P, Mangala S, Grinton Josvi Veigas, Ravikumar R · pp. 217–220Original ArticleSame type: Article