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Indian Journal of Pharmacy PracticeNOW IN
Review

Understanding Artificial Sweeteners and Food Colorants-their Impact on Human Health: A Review

Satish Kumar Basattikoppalu Puttegowda1, Mohith Shivaramu1★, Balaji Skanda Manjunath1, Rajesh Venkataraman1, Ravindra Basaralu Nagarajappa1★ Corresponding author

  1. 1Department of Pharmacy Practice, Faculty of Pharmacy, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, Karnataka, INDIA..

CORRESPONDENCE

Mohith Shivaramu

Department of Pharmacy Practice, Faculty of Pharmacy, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B. G. Nagara, Karnataka, INDIA..

mohiths8055@gmail.com

Received: 10-08-2024; Revised: 13-08-2024; Accepted: 26-08-2024.

Volume 18, Issue 1 · pp. 8–15 · PUBLISHED · DOI: 10.5530/ijopp.20250089

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ABSTRACT

This review article comprehensively explores the overview of artificial sweeteners and food colorants, examining their safety, regulatory status, and potential health effects. It explores the historical background of artificial sweeteners, covering key compounds like saccharin, aspartame and cyclamate, while also highlighting emerging alternatives such as rare sugars. The discussion extends to the physiological impacts of artificial sweeteners including their potential ill effects on blood glucose levels, obesity, gut microbiome, cardiovascular health, and cancer risk. Additionally, the review evaluates the safety and adverse effects of food colorants, emphasizing regulatory frameworks and potential health risks associated with synthetic food colorants like tartrazine and rhodamine B. It concludes by underlining the importance of cautious consumption, particularly among vulnerable populations like children and pregnant women, and advocates for ongoing research to inform evidence-based dietary guidelines and regulatory policies.

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    Puttegowda, S. K. B., Shivaramu, M., Manjunath, B. S., Venkataraman, R., & Nagarajappa, R. B. (). Understanding Artificial Sweeteners and Food Colorants-their Impact on Human Health: A Review. Indian Journal of Pharmacy Practice, 18(1), 8–15. https://doi.org/10.5530/ijopp.20250089