A Prospective Study on HbA1c, Lipid Profile and Genitourinary Infections in Controlled Versus Uncontrolled Diabetic Patients

ABSTRACT

Background:Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, leading to significant metabolic complications. Poor glycemic control exacerbates these complications, including alterations in lipid profiles and an increased susceptibility to infections, particularly in the genitourinary system. Aim: This study aimed to compare HbA1c levels, lipid profiles and the prevalence of genitourinary infections in patients with controlled (HbA1c<7.0%) versus uncontrolled (HbA1c≥7.0%) Type 2 Diabetes Mellitus (T2DM). Materials and Methods: A prospective observational study was conducted at a tertiary care hospital, involving 120 patients diagnosed with T2DM. Participants were divided into two groups based on their HbA1c levels: controlled and uncontrolled. Data on HbA1c, lipid profiles and the occurrence of genitourinary infections were collected and analyzed.Results: The study included 120 participants, comprising 45.83% males and 54.17% females, with a mean age of 62.52 years. The mean HbA1c was 9.15%, indicating poor glycemic control; 73.33% of participants were in the uncontrolled group, with a mean HbA1c of 10.16%, while 26.66% were in the controlled group, with a mean HbA1c of 6.35%. Fasting Blood Glucose (FBG) levels in females ranged from 78 to 786 mg/dL, with a mean of 185.76 mg/dL, whereas in males, the range was 68 to 270 mg/dL, with a mean of 151.94 mg/dL. Conclusion:These findings emphasize the importance of maintaining stringent glycemic control in diabetic patients to optimize lipid profiles and reduce the risk of genitourinary infections. Effective management of HbA1c is crucial for mitigating these associated risks in T2DM patients.

KEYWORDS

• HbA1c
• Lipid Profile
• Genitourinary Infections
• Diabetes mellitus

Showing references and in-text citations exactly as published.

• DOI10.5530/ijopp.20250186Copy

RELATED ARTICLES

Matched on section and article type within this issue of IJPP.

• Article · VOLUME 18, ISSUE 3A Study of Cost Comparison in Anti-Hypertensive Drugs between Jan Aushadhi’s Generic Drugs and Branded DrugsJ. Christy Immaculate · pp. 266–272Original ArticleSame type: Article
• Article · VOLUME 18, ISSUE 3Statistical Insight into CVD Risk Prevalence Among the Cardiac Patients in Jharkhand, IndiaAnushil Anand, Prakash Kumar, Pritam Lenka, Sajalendu Ghosh · pp. 285–290Original ArticleSame type: Article
• Article · VOLUME 18, ISSUE 3Assessment of Cost of Illness and Satisfaction with Life in Hypothyroidism Patients at Tertiary Care Centre, Erode- A Prospective Observational StudySrinivasan S, Hema Nandhini, Arul Prakasam, Senthil Kumar · pp. 291–298Original ArticleSame type: Article
• Article · VOLUME 18, ISSUE 3Enhancing Type 2 Diabetes Management through Patient-Centric Pharmacist Counselling: A Comprehensive StudyThanuji Fernando, Chathula Munasinghe, Hasitha Liyanaarachchi, Rumesh Nelumdeniya, Rohini Fernandopulle · pp. 299–307Original ArticleSame type: Article