An Overview on Paclitaxel in Advanced Chemotherapy
Subash V1★, Venkateswarlu B1, Fareedullah Md1, Sudhakar Y1★ Corresponding author
- 1Department of Pharmacy Practice, MGM Hospital, Warangal, A.P, India.
CORRESPONDENCE
Subash V
Department of Pharmacy Practice, MGM Hospital, Warangal, A.P, India.
Received: 22-07-2010; Accepted: 03-09-2010.
Volume 3, Issue 3 · pp. 1–7 · PUBLISHED · DOI:
ABSTRACT
Paclitaxel is a new cytotoxic agent that has demonstrated significant activity in advanced ovarian, breast, lung, head and neck cancer. The chemotherapy remains problematic and ineffective because of the problems of poor efficacy, parasite resistance, high toxicity, high cost and unavailability of drug in larger hospital. Therefore there is an urgent need for review drug therapy and efficacious of paclitaxel. We developed a search engine to find any literature about pharmacokinetic parameters of paclitaxel and its drug treatment in DOAJ database, Science Direct, and PubMed using the key phrases paclitaxel; drug therapy; adverse drug reactions and pharmacokinetics. Our results shows that efficacy, neurotoxicity and application of paclitaxel. Hence our review concludes that, about the importance and implementation of therapeutic drug monitoring in individualization of chemotherapy in various cancer patients.
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V, S., B, V., Md, F., & Y, S. (). An Overview on Paclitaxel in Advanced Chemotherapy. Indian Journal of Pharmacy Practice, 3(3), 1–7.