An Overview on the Insulin Preparations and Devices
Shery Jacob1★, Mohamed Aly Morsy2,3, Anroop Nair3★ Corresponding author
- 1Department of Pharmaceutics, College of Pharmacy, Gulf Medical University, Ajman, UAE.
- 2Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia, EGYPT.
- 3Department of Pharmaceutics, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, SAUDI ARABIA.
CORRESPONDENCE
Shery Jacob
Department of Pharmaceutics, College of Pharmacy, Gulf Medical University, Ajman, UAE.
Received: 09-03-2018; Revised: 13-04-2018; Accepted: 17-05-2018.
Volume 52, Issue 4 · pp. 550–557 · PUBLISHED 2018 · DOI: 10.5530/ijper.52.4.64
ABSTRACT
Insulin preparations are the mainstay in the management of type 1 along with various type 2 diabetes. Available insulin preparations are either short-acting or long-acting or mixture to mimic the physiological insulin secretion and their doses need to be individualized. Attempting to imitate normal secretion of insulin can be valuable paradigm for understanding and providing effective therapy. This review provides an outline about the composition, use, route of administration, injection site, pharmacokinetics, storage and handling of various insulin preparations. The efficacy and safety of various insulin preparations for the management of diabetes mellitus are discussed. In addition, the use and application of various insulin devices to improve adherence and provide optimum delivery are elaborated. Indeed, the patient awareness and adherence on these issues is crucial to achieve good glycemic control.
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Jacob, S., Morsy, M. A., & Nair, A. (2018). An Overview on the Insulin Preparations and Devices. Indian Journal of Pharmaceutical Education and Research, 52(4), 550–557. https://doi.org/10.5530/ijper.52.4.64