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Indian Journal of Pharmaceutical Education and ResearchNOW IN
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IJPER · Lens · Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug

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Article · Volume 57, Issue 3S · pp. s724–s733

Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug

Dibya Sundar Panda1, Madhusmruti Khandai2

  1. 1Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.
  2. 2Departments of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur, Odisha, INDIA.

Abstract

Background: Natural biopolymers or hydrogels are explored to sustain release of water-soluble drugs.Materials and Methods: Mucilage was isolated from Salvia hispanica seeds. Gelispheres loaded with Losartan Potassium (LP) were prepared using sodium alginate, pectin and CSM.Results: Isolated mucilage possesses immense properties like consistency and excellent hydration. Developed gelispheres exhibited good mucoadhesion and sustained drug release.Conclusion: Findings advocate the use of mucilage for twice daily losartan potassium sustain release system.

Keywords: Chia seed mucilage; Gelisphere; Mucoadhesion

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