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Indian Journal of Pharmaceutical Education and ResearchNOW IN
Article

Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug

Dibya Sundar Panda1★, Madhusmruti Khandai2★ Corresponding author

  1. 1Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.
  2. 2Departments of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur, Odisha, INDIA.

CORRESPONDENCE

Dibya Sundar Panda

Jouf University, Sakaka, Aljouf, SAUDI ARABIA.

dspanda@ju.edu.sa

Received: 14-09-2022; Revised: 05-01-2023; Accepted: 08-06-2023.

Volume 57, Issue 3S · pp. s724–s733 · PUBLISHED 2023 · DOI: 10.5530/ijper.57.3s.82

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ABSTRACT

Background: Natural biopolymers or hydrogels are explored to sustain release of water-soluble drugs. Materials and Methods: Mucilage was isolated from Salvia hispanica seeds. Gelispheres loaded with Losartan Potassium (LP) were prepared using sodium alginate, pectin and CSM. Results: Isolated mucilage possesses immense properties like consistency and excellent hydration. Developed gelispheres exhibited good mucoadhesion and sustained drug release. Conclusion: Findings advocate the use of mucilage for twice daily losartan potassium sustain release system.

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    Panda, D. S., & Khandai, M. (2023). Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug. Indian Journal of Pharmaceutical Education and Research, 57(3S), s724–s733. https://doi.org/10.5530/ijper.57.3s.82