Volume 10, Issue 1

Amit Gupta, Tapan Behl, Arun Kumar, Sukhbir Singh, Shaveta Bhardwaj, Amit Goyal

pp. 1–7 · DOI: 10.5530/ijpi.2020.1.1 · 2020

Diabetes is one of the most prevalent disease worldwide and is associated with one of the highest morbidities and mortality rates associated. Like the western and conventional medicines, Traditional Chinese medicine (TCM…

Ravikumar Tamil Ponni, Mahalingam Swamivelmanickam, Sivagnanam Sivakrishnan

pp. 8–12 · DOI: 10.5530/ijpi.2020.1.2 · 2020

Three-dimensional printing is a revolutionary technique that uses computer aided design software and programming to create three dimensional objects by placing material on a substrate. 3D printing is an additive layer ma…

Harmita H, Herman Suryadi, Mohdar Syarif, Lidwina Deviani Liksasa

pp. 17–23 · DOI: 10.5530/ijpi.2020.1.4 · 2020

Background: Diallyl disulphide (DADS) and diallyl trisulphide (DATS) found in garlic provide biological activity which protects against oxidative damage. This study aimed to confirm the presence of DADS and DATS compound…

Arora Rimpi, Deshmukh Rahul

pp. 24–31 · DOI: 10.5530/ijpi.2020.1.5 · 2020

Background:With the constant failure of the clinical trials and continuous exploration of a therapeutic target against Alzheimer’s disease (AD) is the utmost needed. Chebulinic acid (ChA) has been reported to possess neu…

Syed Imam Rabbani

pp. 32–36 · DOI: 10.5530/ijpi.2020.1.6 · 2020

Objectives:The aim of the study is to evaluate the anxiolytic and antidepressant activity of Salvadora persica in cigarette smoke-induced neurobehavior changes in rats. Methods:The lyophilized decoction of Salvadora pers…

Alok Kumar Soni, Uma Pathak, Durga Prasad Nagar, Arvind Kumar Gupta, Gurusamy Mathu Kannan

pp. 37–42 · DOI: 10.5530/ijpi.2020.1.7 · 2020

Aim:The present study was undertaken to investigate the comparative pulmonary protective efficacy of Amifostine (S-2[3-aminoprophylamino] ethyl phosphorothioate) and its analogues DRDE-07 (S-2(2-aminoethylamino) ethyl ph…

Rai Pratikcha, Das Sujit, Ghosh Tanmoy, Deveswaran Rajamanickam, Mohanta Tanmay, Roy Kalyan

pp. 43–48 · DOI: 10.5530/ijpi.2020.1.8 · 2020

Objectives: Sheep butter has been traditionally used in the local villages of upper Himalayan region for its various dermatological benefits. In the current study, sheep butter cream was formulated and evaluated for its …

Haritha P, Lakshmi PK

pp. 49–53 · DOI: 10.5530/ijpi.2020.1.9 · 2020

Objective: Probilosomes vesicular drug delivery system was developed to prevent acid degradation of the drug and to improve its oral bioavailability by resisting the drug release in acidic pH of the stomach. Method: Thin…

Srinivasa Rao Baratam, Made Vijay Harsha

pp. 54–58 · DOI: 10.5530/ijpi.2020.1.10 · 2020

Objective:The major objective of this work is to formulate a sustained launch matrix drugs the use of cashew and neem gum. Ketoprofen turned into decided on as a version drug because of the low half-life. Hence sustained…

Radha Rani Earle, Vanthala Vijaya Bharathi, Ayalasomayajula Lakshmi Usha, Andhavarapu Venkata Srinivasa Ksheera Bhavani

pp. 59–63 · DOI: 10.5530/ijpi.2020.1.11 · 2020

Objectives:This research was aimed to evaluate a novel approach for preparation of mucoadhesive microspheres which can reside in the gastrointestinal tract for an extended time period. The microspheres contained amoxicil…

Mohammed Maher Mehanna

pp. 64–69 · DOI: 10.5530/ijpi.2020.1.12 · 2020

Objectives: The aim of current research was to formulate limonene selfnanoemulsified delivery system (SNEDS) by spontaneous emulsification method. Methods:The optimization was carried out through the construction of a ps…

Sumanta Mondal, Arindam Pal, Prasenjit Mondal, Dipankar Shit, Sabyasachi Biswal, Beemarasetti Mohan Babu

pp. 70–75 · DOI: 10.5530/ijpi.2020.1.13 · 2020

Objectives: The present research work involve the development of a novel UV-Spectrophotometric and stability-indicating RP-HPLC methods for the irbesartan in bulk as well as tablet dosage form. Methods:The RP-HPLC method…

Shailesh Koradia, Priyal Patel, Ashok Mahajan, Falgun Mehta, Vishwa Chauhan

pp. 76–81 · DOI: 10.5530/ijpi.2020.1.14 · 2020

Objectives:A precise, accurate and selective stability-indicating reverse phase high performance liquid chromatographic assay method has been developed for the simultaneous quantitative determination of Montelukast sodiu…

Mohammed Maher Mehanna

pp. 82–85 · DOI: 10.5530/ijpi.2020.1.15 · 2020

Objectives: Electrospun Cellulose Acetate (CA) fibers system are of high demand due to its desired properties associated with the final fiber features. This polymer inability to dissolve may hinder its electrospinning pr…

Apichart Atipairin, Somchai Sawatdee

pp. 93–95 · DOI: 10.5530/ijpi.2020.1.17 · 2020

Background:Sildenafil citrate is a drug used in the treatment of pulmonary hypertension. The development of sildenafil citrate complexed with α-cyclodextrin as dry powder inhaler (DPI) should enhance its solubility in th…