Volume 10, Issue 2

Seema S Rathore, Geetha M, S Ramachandra Setty

pp. 96–105 · DOI: 10.5530/ijpi.2020.2.18 · 2020

Development of safe and efficacious gastro-retentive dosage forms for stomach specific drug delivery have profound importance in pharmaceutical industry. Different approaches used for gastro retention are discussed with …

Davoud Balarak, Aram Dokht Khatibi, Kethineni Chandrika

pp. 106–111 · DOI: 10.5530/ijpi.2020.2.19 · 2020

With the widespread use of antibiotics, pharmaceutical effluents containing antibiotics have recently attracted wide attentions since it has potential adverse effects. Although the injuriousness of antibiotics is not so …

Bharat Mishra, MV Akhila, Ann Thomas, Biliya Benny, Hiba Assainar

pp. 112–116 · DOI: 10.5530/ijpi.2020.2.20 · 2020

In the traditional system of practices, animal fats and its oil gained acceptance in healing various ailments. Fats are chemically triglycerides in which glycerol is esterified with three fatty acids. The fats are genera…

Tina Rostinawati, Nadia Gitta Paramita, Imam Adi Wicaksono, Sriwidodo S, Muhammad Yusuf, Toto Subroto

pp. 117–121 · DOI: 10.5530/ijpi.2020.2.21 · 2020

Objectives: In patients with breast cancer, Human Epidermal Growth Factor is over expressed until 30%. Monoclonal antibodies was an alternative detection cancer in molecular level. The aim of the experiment was protein r…

Davoud Balarak, Fatemeh Ganji, Kethineni Chandrika, Shaziya Haseeb

pp. 122–126 · DOI: 10.5530/ijpi.2020.2.22 · 2020

Objectives: In this article, novel montmorillonite nanoparticles (MON-NP) evaluated in order to facilitatethe sorption of Amoxicillin (AMO) from aqueous solutions in batch operations. Methods:Batch experiments were perfo…

Kaliyamoorthy Jayabalan, Arangasamy Magesh, Rajan Rajeshkannan, Palani Rathakrishnan

pp. 127–131 · DOI: 10.5530/ijpi.2020.2.23 · 2020

Objectives: The present work is focused on the sensory quality of yogurt produced with high fibre powder. Methods: Response surface methodology (RSM) was used to optimize the ingredients like: Milk (1000 ml), sugar (100 …

Reyaz Hassan Mir, Mubashir Hussain Masoodi

pp. 132–135 · DOI: 10.5530/ijpi.2020.2.24 · 2020

Background: Origanum vulgare is a perennial shrub that grows in the mountains of the Mediterranean and Euro/Iran-Siberian regions. Objectives:This study was conducted to identify the major constituents of the ethanolic e…

Ekramul Haque, Saqib Hassan

pp. 136–140 · DOI: 10.5530/ijpi.2020.2.25 · 2020

Background: Biosurfactants are the surface-active molecules produced by the living micro-organisms. They have wide application in the food, cosmetic, pharmaceutical and petrochemical industry due to its physiological and…

Jasvin Singh, Rasvin Singh, Subramani Parasuraman, Sathasivam Kathiresan

pp. 141–145 · DOI: 10.5530/ijpi.2020.2.26 · 2020

Objective:To investigate the antimicrobial activities of various solvent extracts of the bark of Cinnamomum cassia and Cinnamomum zeylanicum. Methods: The powdered barks of C. cassia and C. zeylanicum were extracted usin…

Ganeshan Pradheesh, Santhanam Suresh, Joghee Suresh, Vincent Alexramani

pp. 146–150 · DOI: 10.5530/ijpi.2020.2.27 · 2020

Objectives:To synthesize silver oxide nanoparticles from the medicinal plantCyathea nilgiriensis Holttum and to evaluate the percentage of inhibition of silver oxide nanoparticles against some selective bacterial species…

Ashok Mahajan, Priyal Patel, Nimisha Kareliya

pp. 151–155 · DOI: 10.5530/ijpi.2020.2.28 · 2020

Objectives: The objective of present study was to formulate and optimize ophthalmic pH triggered in situ gelling system of tobramycin in order to enhance residence time and provide prolonged drug release. Methods: Two fa…

Shivendra Agarwal, Girendra Gautam

pp. 156–159 · DOI: 10.5530/ijpi.2020.2.29 · 2020

Objectives:The main objective of the present investigation was to develop transdermal delivery of Atorvastatin, a HMG-CoAreductase inhibitor used in the treatment of congestive heart failure (CHF). Atorvastatin was formu…

SR Suseem, Dhanish Joseph

pp. 160–166 · DOI: 10.5530/ijpi.2020.2.30 · 2020

Background: Multi-particulate drug delivery systems are mainly oral dosage forms consisting of a multiplicity of small discrete units, each exhibiting some desired characteristics. Duloxetine hydrochloride is acid-labile…

Mukesh Kumar, Swaroop Rameshwarji Lahoti

pp. 167–172 · DOI: 10.5530/ijpi.2020.2.31 · 2020

Objective:The objective of the present study was to prepare tacrolimus liposomal gel formulations using ethanolic injection technique for efficacious and cost-effective treatment of atopic dermatitis. Methods: The liposo…

Ekramul Haque, K Kayalvizhi, Saqib Hassan

pp. 173–178 · DOI: 10.5530/ijpi.2020.2.32 · 2020

Objective:In this study, the biosurfactant, produced by a potent non-pathogenic bacterial strain of Marinobacter litoralis MB15 was used for anti-microbial, anti-oxidant and biocompatibility assay. Materials and Methods:…

Suvarna Chittam, Ashok Bhosale

pp. 179–183 · DOI: 10.5530/ijpi.2020.2.33 · 2020

Objectives:Furosemide is BCS class IV drug which shows pH dependent solubility and permeability. It is very poorly soluble in stomach medium (0.006 mg/mL) and having high permeability through stomach, but its solubility …

Suhas Marutirao Kakade, Dehghan Mohamed Hassan

pp. 184–191 · DOI: 10.5530/ijpi.2020.2.34 · 2020

Objectives: The present work relates with developing long acting controlled release poly(DL-lactide-co-glycolic acid) (PLGA) microspheres of Goserelin acetate for treatment of breast and prostate cancer. Methods: Microsp…

Furquan Nazimuddin Khan, Zahid Zaheer, Moizul Hasan, Imran Anees, Sarfaraz Khan, Iftequar Syed, Priti Sanjay Puranik

pp. 192–196 · DOI: 10.5530/ijpi.2020.2.35 · 2020

Background:Rosuvastatin calcium is the most effective molecule for the treatment and management of Hypercholesterolemia. This drug easily degrades by exposure to moisture and light and forms unstable formulation by forma…

Sumanta Mondal, Reddipalli Pushpalatha, Prasenjit Mondal, Ashes Sinha Mahapatra, Dipankar Shit, Anik Kumar Das, Sabyasachi Biswal

pp. 197–201 · DOI: 10.5530/ijpi.2020.2.36 · 2020

Objective:An accurate reverse phase High Performance liquid chromatography (RP-HPLC) method has been developed, validated and applied to stability indicating studies to determine Lercanidipine HCl in dosage form. Methods…

Kanala Somasekhar Reddy, Pamisetty Likithasree, Ramlingam Peraman, Mallela Vijaya Jyothi, Chilamakuru Naresh Babu, Bhupalam Pradeepkumar, Akkiraju Sudheer

pp. 202–207 · DOI: 10.5530/ijpi.2020.2.37 · 2020

Objectives: Alzheimer’s disease is a leading neurodegenerative disorders having serious effect on an individual’s occupational potential and quality of life. The natural and nutritional based remedy is continuing interes…