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International Journal of Pharmaceutical InvestigationNOW IN
Article

Antimicrobial Activity of Extracts of Bark of Cinnamomum cassia and Cinnamomum zeylanicum

Jasvin Singh1, Rasvin Singh1, Subramani Parasuraman2★, Sathasivam Kathiresan1★ Corresponding author

  1. 1Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Kedah, MALAYSIA.
  2. 2Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Kedah, MALAYSIA.

CORRESPONDENCE

Subramani Parasuraman

Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Kedah, MALAYSIA.

parasuphd@gmail.com

Received: 28-03-2020; Revised: 15-04-2020; Accepted: 02-05-2020.

Volume 10, Issue 2 · pp. 141–145 · PUBLISHED · DOI: 10.5530/ijpi.2020.2.26

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ABSTRACT

Objective:To investigate the antimicrobial activities of various solvent extracts of the bark of Cinnamomum cassia and Cinnamomum zeylanicum. Methods: The powdered barks of C. cassia and C. zeylanicum were extracted using methanol, ethanol and acetone. The antimicrobial activity of methanolic, ethanolic and acetone extracts of barks of C. cassia and C. zeylanicum were studied using agar well diffusion method against seven ATCC bacterial species (Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis, Streptococcus pyogenes, Escherichia coli, Salmonella bongori and Pseudomonas aeruginosa). The antimicrobial activity of extracts of C. cassia and C. zeylanicum were compared with gentamycin. Results:The ethanolic and acetone extract of C. cassia and C. zeylanicum showed greater zones of inhibition than methanolic extract. C. zeylanicum inhibited the growth of all seven ATCC strains used in this study whereas, C. cassia inhibited the growth of S. pyogenes, S. aureus, B. cereus, E. faecalis, P. aeruginosa and S. bongori. Gentamycin inhibited the pathogenic group of all ATCC strains used in this study. Conclusion: The ethanolic and acetone extracts of bark of C. Cassia and C. zeylanicum exhibited a broad spectrum of exhibited a broad-spectrum antimicrobial activity.

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    Singh, J., Singh, R., Parasuraman, S., & Kathiresan, S. (). Antimicrobial Activity of Extracts of Bark of Cinnamomum cassia and Cinnamomum zeylanicum. International Journal of Pharmaceutical Investigation, 10(2), 141–145. https://doi.org/10.5530/ijpi.2020.2.26