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International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 10, issue 2 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 10, Issue 2

· pp. 96–232 · 25 articles

Volume
10
Issue
2
Published
Pages
96–232
Articles
25
Sections
2
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal Article

In this issue

Review Article

  1. Review

    Natural Polysaccharides: An Overview of their Role in the Development of Microparticles for Stomach Targeting

    Seema S Rathore, Geetha M, S Ramachandra Setty

    pp. 96–105 · DOI: 10.5530/ijpi.2020.2.18 · Published

    Development of safe and efficacious gastro-retentive dosage forms for stomach specific drug delivery have profound importance in pharmaceutical industry. Different approaches used for gastro retention are discussed with …

  2. Review

    Antibiotics Removal from Aqueous Solution and Pharmaceutical Wastewater by Adsorption Process: A Review

    Davoud Balarak, Aram Dokht Khatibi, Kethineni Chandrika

    pp. 106–111 · DOI: 10.5530/ijpi.2020.2.19 · Published

    With the widespread use of antibiotics, pharmaceutical effluents containing antibiotics have recently attracted wide attentions since it has potential adverse effects. Although the injuriousness of antibiotics is not so …

  3. Review

    Formulated Therapeutic Products of Animal Fats and Oils: Future Prospects of Zootherapy

    Bharat Mishra, MV Akhila, Ann Thomas, Biliya Benny, Hiba Assainar

    pp. 112–116 · DOI: 10.5530/ijpi.2020.2.20 · Published

    In the traditional system of practices, animal fats and its oil gained acceptance in healing various ailments. Fats are chemically triglycerides in which glycerol is esterified with three fatty acids. The fats are genera…

Original Article

  1. Article

    Characterization of Anti-HER2 scFv Gene Expression as Intracellular Protein in Escherichia coli BL21 (DE3)

    Tina Rostinawati, Nadia Gitta Paramita, Imam Adi Wicaksono, Sriwidodo S, Muhammad Yusuf, Toto Subroto

    pp. 117–121 · DOI: 10.5530/ijpi.2020.2.21 · Published

    Objectives: In patients with breast cancer, Human Epidermal Growth Factor is over expressed until 30%. Monoclonal antibodies was an alternative detection cancer in molecular level. The aim of the experiment was protein r…

  2. Article

    Montmorillonite Nanoparticles Effectiveness in Removal of Amoxicillin from Water Solutions

    Davoud Balarak, Fatemeh Ganji, Kethineni Chandrika, Shaziya Haseeb

    pp. 122–126 · DOI: 10.5530/ijpi.2020.2.22 · Published

    Objectives: In this article, novel montmorillonite nanoparticles (MON-NP) evaluated in order to facilitatethe sorption of Amoxicillin (AMO) from aqueous solutions in batch operations. Methods:Batch experiments were perfo…

  3. Article

    Fortification of Fibre in Yogurt using High Fibre Banana Stem and Jack Fruit Powder

    Kaliyamoorthy Jayabalan, Arangasamy Magesh, Rajan Rajeshkannan, Palani Rathakrishnan

    pp. 127–131 · DOI: 10.5530/ijpi.2020.2.23 · Published

    Objectives: The present work is focused on the sensory quality of yogurt produced with high fibre powder. Methods: Response surface methodology (RSM) was used to optimize the ingredients like: Milk (1000 ml), sugar (100 …

  4. Article

    Phytochemical Screening and Liquid Chromatography-Mass Spectrometry Studies of Ethyl Acetate Extract of Origanum vulgare

    Reyaz Hassan Mir, Mubashir Hussain Masoodi

    pp. 132–135 · DOI: 10.5530/ijpi.2020.2.24 · Published

    Background: Origanum vulgare is a perennial shrub that grows in the mountains of the Mediterranean and Euro/Iran-Siberian regions. Objectives:This study was conducted to identify the major constituents of the ethanolic e…

  5. Article

    Physiochemical Characterization and Anti-colon Cancer Activity of Biosurfactant Produced from Marine Pseudomonas sp.

    Ekramul Haque, Saqib Hassan

    pp. 136–140 · DOI: 10.5530/ijpi.2020.2.25 · Published

    Background: Biosurfactants are the surface-active molecules produced by the living micro-organisms. They have wide application in the food, cosmetic, pharmaceutical and petrochemical industry due to its physiological and…

  6. Article

    Antimicrobial Activity of Extracts of Bark of Cinnamomum cassia and Cinnamomum zeylanicum

    Jasvin Singh, Rasvin Singh, Subramani Parasuraman, Sathasivam Kathiresan

    pp. 141–145 · DOI: 10.5530/ijpi.2020.2.26 · Published

    Objective:To investigate the antimicrobial activities of various solvent extracts of the bark of Cinnamomum cassia and Cinnamomum zeylanicum. Methods: The powdered barks of C. cassia and C. zeylanicum were extracted usin…

  7. Article

    Antimicrobial and Anticancer Activity Studies on Green Synthesized Silver Oxide Nanoparticles from the Medicinal Plant Cyathea nilgiriensis Holttum

    Ganeshan Pradheesh, Santhanam Suresh, Joghee Suresh, Vincent Alexramani

    pp. 146–150 · DOI: 10.5530/ijpi.2020.2.27 · Published

    Objectives:To synthesize silver oxide nanoparticles from the medicinal plantCyathea nilgiriensis Holttum and to evaluate the percentage of inhibition of silver oxide nanoparticles against some selective bacterial species…

  8. Article

    Ophthalmic pH Triggered in situ Gelling System of Tobramycin: Formulation and Optimization using Factorial Design

    Ashok Mahajan, Priyal Patel, Nimisha Kareliya

    pp. 151–155 · DOI: 10.5530/ijpi.2020.2.28 · Published

    Objectives: The objective of present study was to formulate and optimize ophthalmic pH triggered in situ gelling system of tobramycin in order to enhance residence time and provide prolonged drug release. Methods: Two fa…

  9. Article

    Formulation, Development and Characterization of Ethosomes of Atorvastatin

    Shivendra Agarwal, Girendra Gautam

    pp. 156–159 · DOI: 10.5530/ijpi.2020.2.29 · Published

    Objectives:The main objective of the present investigation was to develop transdermal delivery of Atorvastatin, a HMG-CoAreductase inhibitor used in the treatment of congestive heart failure (CHF). Atorvastatin was formu…

  10. Article

    Formulation Development and Evaluation of Duloxetine Hydrochloride Multi-Particulate Delayed-Release Capsules

    SR Suseem, Dhanish Joseph

    pp. 160–166 · DOI: 10.5530/ijpi.2020.2.30 · Published

    Background: Multi-particulate drug delivery systems are mainly oral dosage forms consisting of a multiplicity of small discrete units, each exhibiting some desired characteristics. Duloxetine hydrochloride is acid-labile…

  11. Article

    Development and Characterization of Tacrolimus Liposomal Gel for Industrial Application

    Mukesh Kumar, Swaroop Rameshwarji Lahoti

    pp. 167–172 · DOI: 10.5530/ijpi.2020.2.31 · Published

    Objective:The objective of the present study was to prepare tacrolimus liposomal gel formulations using ethanolic injection technique for efficacious and cost-effective treatment of atopic dermatitis. Methods: The liposo…

  12. Article

    Biocompatibility, Antioxidant and Anti-Infective Effect of Biosurfactant Produced by Marinobacter litoralis MB15

    Ekramul Haque, K Kayalvizhi, Saqib Hassan

    pp. 173–178 · DOI: 10.5530/ijpi.2020.2.32 · Published

    Objective:In this study, the biosurfactant, produced by a potent non-pathogenic bacterial strain of Marinobacter litoralis MB15 was used for anti-microbial, anti-oxidant and biocompatibility assay. Materials and Methods:…

  13. Article

    Development and Evaluation of Floating and Expanding Gastroretentive Film of Furosemide

    Suvarna Chittam, Ashok Bhosale

    pp. 179–183 · DOI: 10.5530/ijpi.2020.2.33 · Published

    Objectives:Furosemide is BCS class IV drug which shows pH dependent solubility and permeability. It is very poorly soluble in stomach medium (0.006 mg/mL) and having high permeability through stomach, but its solubility …

  14. Article

    Formulation and in vitro / in vivo Evaluation of Novel Biodegradable Microspheres for Treatment of Hormone Responsive Cancers

    Suhas Marutirao Kakade, Dehghan Mohamed Hassan

    pp. 184–191 · DOI: 10.5530/ijpi.2020.2.34 · Published

    Objectives: The present work relates with developing long acting controlled release poly(DL-lactide-co-glycolic acid) (PLGA) microspheres of Goserelin acetate for treatment of breast and prostate cancer. Methods: Microsp…

  15. Article

    Stabilization of Rosuvastatin Calcium Formulation by Prevention of Intermolecular Esterification: An Experimental Design

    Furquan Nazimuddin Khan, Zahid Zaheer, Moizul Hasan, Imran Anees, Sarfaraz Khan, Iftequar Syed, Priti Sanjay Puranik

    pp. 192–196 · DOI: 10.5530/ijpi.2020.2.35 · Published

    Background:Rosuvastatin calcium is the most effective molecule for the treatment and management of Hypercholesterolemia. This drug easily degrades by exposure to moisture and light and forms unstable formulation by forma…

  16. Article

    A Stability Indicating Validated Method for the Determination of Lercanidipine Using Reverse Phase High Performance Liquid Chromatography

    Sumanta Mondal, Reddipalli Pushpalatha, Prasenjit Mondal, Ashes Sinha Mahapatra, Dipankar Shit, Anik Kumar Das, Sabyasachi Biswal

    pp. 197–201 · DOI: 10.5530/ijpi.2020.2.36 · Published

    Objective:An accurate reverse phase High Performance liquid chromatography (RP-HPLC) method has been developed, validated and applied to stability indicating studies to determine Lercanidipine HCl in dosage form. Methods…

  17. Article

    Spatial Long-Term Memory Retention by Banana and Papaya Peel Extract: In silico and in vivo Evaluation

    Kanala Somasekhar Reddy, Pamisetty Likithasree, Ramlingam Peraman, Mallela Vijaya Jyothi, Chilamakuru Naresh Babu, Bhupalam Pradeepkumar, Akkiraju Sudheer

    pp. 202–207 · DOI: 10.5530/ijpi.2020.2.37 · Published

    Objectives: Alzheimer’s disease is a leading neurodegenerative disorders having serious effect on an individual’s occupational potential and quality of life. The natural and nutritional based remedy is continuing interes…

  18. Article

    Renoprotective Effects of Valsartan And Amlodipine in a Nephrotoxic Model of Experimental Animals

    Doa’a Anwar Ibrahim, Ahmed Al-mohamady

    pp. 208–210 · DOI: 10.5530/ijpi.2020.2.38 · Published

    Background: Calcium channel blockers and AT1 antagonists have efficacious effects to control elevated blood pressure by different mechanisms. They are used widely in co-morbid hypertensive patients either to prevent dete…

  19. Article

    Combination of Docetaxel with Thymoquinone in Nanoemulsion Impedes the Migration of Breast Cancer Stem Cells

    Bawadud RS, Mayson H Alkhatib, Gashlan HM

    pp. 211–216 · DOI: 10.5530/ijpi.2020.2.39 · Published

    Objectives:Metastatic breast cancer is an advanced stage that is highly dependent on migration signaling pathways, though it remains unclear what mechanisms control the maintenance of tumorigenic cells that drives the mi…

  20. Article

    Efficacy and Safety of Inhaled Indacaterol and Tiotropium in Patients of Chronic Obstructive Pulmonary Disease

    Mohammad Sajid Alam, Jameel Ahmad, Anil Kumar, Mohammad Shameem

    pp. 217–220 · DOI: 10.5530/ijpi.2020.2.40 · Published

    Introduction: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide. Indacaterol is a new once daily inhaled bronchodilator, recently approved for the treatment of COPD. Once daily do…

  21. Article

    Treatment Pattern and Awareness of Migraine in Eastern Provinces, Saudi Arabia: A Descriptive Cross Sectional Study

    Ayaz Ahmad, Mohammad Daud Ali, Yousif Amin Mohamed Hassan, Reemah Shabak Al Dhefairy, Samar Thamer Al Saad, Rahmah Jassim Al Khalifa

    pp. 221–224 · DOI: 10.5530/ijpi.2020.2.41 · Published

    Objectives:This study aimed is to identify treatment pattern and awareness of migraine in Eastern provinces of Saudi Arabia. Methods: The survey questionnaire used to assess the awareness and treatment pattern of migrain…

  22. Article

    Prevalence, Awareness, Attitudes and Usefulness of Allopolyherbal Medications Among Type 2 Diabetics: A Community Based Cross-sectional Survey

    Bharat Mishra, Anvy Thankachan, Lancy Morries, Sanjana Charly, Basil John, Merin Joshy

    pp. 225–232 · DOI: 10.5530/ijpi.2020.2.42 · Published

    Objectives:The prevalence of herbal medicines is drastically increasing among patients with chronic diseases like diabetes mellitus due to its difficulty in adhering to therapeutic regimens and lifestyle changes, without…