International Journal of Pharmaceutical Investigation
Volume 10, Issue 1
· pp. 1–95 · 17 articles
- Volume
- 10
- Issue
- 1
- Published
- Pages
- 1–95
- Articles
- 17
- Sections
- 3
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
Review Article
- Review
Unexplored Potential of Traditional Chinese Medicine in Diabetes Mellitus
Amit Gupta, Tapan Behl, Arun Kumar, Sukhbir Singh, Shaveta Bhardwaj, Amit Goyal
pp. 1–7 · DOI: 10.5530/ijpi.2020.1.1 · Published
Diabetes is one of the most prevalent disease worldwide and is associated with one of the highest morbidities and mortality rates associated. Like the western and conventional medicines, Traditional Chinese medicine (TCM…
- Review
3D Printing in Pharmaceutical Technology – A Review
Ravikumar Tamil Ponni, Mahalingam Swamivelmanickam, Sivagnanam Sivakrishnan
pp. 8–12 · DOI: 10.5530/ijpi.2020.1.2 · Published
Three-dimensional printing is a revolutionary technique that uses computer aided design software and programming to create three dimensional objects by placing material on a substrate. 3D printing is an additive layer ma…
Original Article
- Article
Pharmacognostic and Phytochemical Characteristics of the Fruits of Bunium persicum (Boiss.) B. Fedtsch, Growing Wild in Kashmir Valley, India
Riehana Gani, Zulfiqar Ali Bhat, Mudasir Ahmad Dar, Mohammad Akbar Dar, Junaid ul Yousuf Rather
pp. 13–16 · DOI: 10.5530/ijpi.2020.1.3 · Published
Introduction:Bunium persicum (Boiss.) B. Fedtsch belongs to family Apiaceae of genus Bunium, which is comprised of about 166 species and is widely distributed in Kashmir valley. It is used medicinally in dyspepsia and di…
- Article
Gas Chromatography Analysis of Diallyl Disulphide and Diallyl Trisulphide and Antioxidant Activity in Black Garlic
Harmita H, Herman Suryadi, Mohdar Syarif, Lidwina Deviani Liksasa
pp. 17–23 · DOI: 10.5530/ijpi.2020.1.4 · Published
Background: Diallyl disulphide (DADS) and diallyl trisulphide (DATS) found in garlic provide biological activity which protects against oxidative damage. This study aimed to confirm the presence of DADS and DATS compound…
- Article
Chebulinic Acid Negated the Development of Streptozotocin- Induced Experimental Dementia in Rats
Arora Rimpi, Deshmukh Rahul
pp. 24–31 · DOI: 10.5530/ijpi.2020.1.5 · Published
Background:With the constant failure of the clinical trials and continuous exploration of a therapeutic target against Alzheimer’s disease (AD) is the utmost needed. Chebulinic acid (ChA) has been reported to possess neu…
- Article
Ameliorative Effect of Salvadora persica (Miswak) on Cigarette Smoke Induced Anxiety and Depression in Rats
Syed Imam Rabbani
pp. 32–36 · DOI: 10.5530/ijpi.2020.1.6 · Published
Objectives:The aim of the study is to evaluate the anxiolytic and antidepressant activity of Salvadora persica in cigarette smoke-induced neurobehavior changes in rats. Methods:The lyophilized decoction of Salvadora pers…
- Article
Comparative Pulmonary Protective Efficacy of Amifostine and it’s Analogue S-2(2-aminoethylamino)ethyl Phenyl Sulfide (DRDE-07) against Sulphur Mustard Induced Oxidative Stress and Inflammation in Female Mice
Alok Kumar Soni, Uma Pathak, Durga Prasad Nagar, Arvind Kumar Gupta, Gurusamy Mathu Kannan
pp. 37–42 · DOI: 10.5530/ijpi.2020.1.7 · Published
Aim:The present study was undertaken to investigate the comparative pulmonary protective efficacy of Amifostine (S-2[3-aminoprophylamino] ethyl phosphorothioate) and its analogues DRDE-07 (S-2(2-aminoethylamino) ethyl ph…
- Article
Development of Sheep Butter Based Cream for Dermal Wound Healing
Rai Pratikcha, Das Sujit, Ghosh Tanmoy, Deveswaran Rajamanickam, Mohanta Tanmay, Roy Kalyan
pp. 43–48 · DOI: 10.5530/ijpi.2020.1.8 · Published
Objectives: Sheep butter has been traditionally used in the local villages of upper Himalayan region for its various dermatological benefits. In the current study, sheep butter cream was formulated and evaluated for its …
- Article
Probilosomes: A Novel Bile Salt Containing Nanocarrier for Enhancing Oral Bioavailability
Haritha P, Lakshmi PK
pp. 49–53 · DOI: 10.5530/ijpi.2020.1.9 · Published
Objective: Probilosomes vesicular drug delivery system was developed to prevent acid degradation of the drug and to improve its oral bioavailability by resisting the drug release in acidic pH of the stomach. Method: Thin…
- Article
Preparation and Characterisation of Sustained Released Dosage Form for Ketoprofen using Natural Gums
Srinivasa Rao Baratam, Made Vijay Harsha
pp. 54–58 · DOI: 10.5530/ijpi.2020.1.10 · Published
Objective:The major objective of this work is to formulate a sustained launch matrix drugs the use of cashew and neem gum. Ketoprofen turned into decided on as a version drug because of the low half-life. Hence sustained…
- Article
Cross-Linked Chitosan Based Stomach Specific Mucoadhesive Microspheres Loaded with Amoxicillin: Preparation and ex vivo Characterization
Radha Rani Earle, Vanthala Vijaya Bharathi, Ayalasomayajula Lakshmi Usha, Andhavarapu Venkata Srinivasa Ksheera Bhavani
pp. 59–63 · DOI: 10.5530/ijpi.2020.1.11 · Published
Objectives:This research was aimed to evaluate a novel approach for preparation of mucoadhesive microspheres which can reside in the gastrointestinal tract for an extended time period. The microspheres contained amoxicil…
- Article
Limonene-based Self-nanoemulsifying System: Formulation, Physicochemical Characterization and Stability
Mohammed Maher Mehanna
pp. 64–69 · DOI: 10.5530/ijpi.2020.1.12 · Published
Objectives: The aim of current research was to formulate limonene selfnanoemulsified delivery system (SNEDS) by spontaneous emulsification method. Methods:The optimization was carried out through the construction of a ps…
- Article
Determination of Irbesartan Using Stability Indicating Reverse Phase Liquid Chromatographic and UV Spectrophotometric Method
Sumanta Mondal, Arindam Pal, Prasenjit Mondal, Dipankar Shit, Sabyasachi Biswal, Beemarasetti Mohan Babu
pp. 70–75 · DOI: 10.5530/ijpi.2020.1.13 · Published
Objectives: The present research work involve the development of a novel UV-Spectrophotometric and stability-indicating RP-HPLC methods for the irbesartan in bulk as well as tablet dosage form. Methods:The RP-HPLC method…
- Article
Separation and Simultaneous Quantitation of Montelukast Sodium and Ebastine in Tablets by using Stability-Indicating Liquid Chromatographic Method
Shailesh Koradia, Priyal Patel, Ashok Mahajan, Falgun Mehta, Vishwa Chauhan
pp. 76–81 · DOI: 10.5530/ijpi.2020.1.14 · Published
Objectives:A precise, accurate and selective stability-indicating reverse phase high performance liquid chromatographic assay method has been developed for the simultaneous quantitative determination of Montelukast sodiu…
- Article
Electrospun Fibrous Mat of Cellulose Acetate: Influence of Solvent System (Acetic Acid/Acetone) on Fibers Morphology
Mohammed Maher Mehanna
pp. 82–85 · DOI: 10.5530/ijpi.2020.1.15 · Published
Objectives: Electrospun Cellulose Acetate (CA) fibers system are of high demand due to its desired properties associated with the final fiber features. This polymer inability to dissolve may hinder its electrospinning pr…
- Article
Pharmacognostic Evaluation of Fruits and Leaves of Annona muricata L
Swapna Birendra, Harisha Ramappa, Satvik Kotha, Raghavendra Rao M, Ramachandra Setty Siddamsetty
pp. 86–92 · DOI: 10.5530/ijpi.2020.1.16 · Published
Objectives:Adulteration in marketed samples has been considered as huge draw-back in fortifying quality herbal products. The study was to investigate and establish leaves, fresh fruit and dry powdered material of pulp, f…
Short Communication
- Communication
Development of Spray-Dried Sildenafil Citrate -α-cyclodextrin Complexes for Use in Dry Powder Inhalers
Apichart Atipairin, Somchai Sawatdee
pp. 93–95 · DOI: 10.5530/ijpi.2020.1.17 · Published
Background:Sildenafil citrate is a drug used in the treatment of pulmonary hypertension. The development of sildenafil citrate complexed with α-cyclodextrin as dry powder inhaler (DPI) should enhance its solubility in th…

