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International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 9, issue 4 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 9, Issue 4

· pp. 148–222 · 14 articles

Volume
9
Issue
4
Published
Pages
148–222
Articles
14
Sections
3
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal ArticleShort Communication

In this issue

Review Article

  1. Review

    Lipid Nanoparticle Topical and Transdermal Delivery: A Review on Production, Penetration Mechanism to Skin

    Dilip Kumar Patel, Roohi Kesharwani, Vikas Kumar

    pp. 148–153 · DOI: 10.5330/ijpi.2019.4.28 · Published

    Nanoparticulate drug delivery systems have an advanced and modern approach over the traditional delivery system. This systematic review on nanoparticulate drug delivery containing lipid and focus on preparation, challeng…

Original Article

  1. Article

    Homology Modelling and Molecular Docking Studies of Interleukin 10 Proteins from Different Species

    Keerthana Pasam, Vaishnavi Mallojala, Shravan Kumar Gunda, Seshagiri Bandi, Mahmood Shaik

    pp. 154–157 · DOI: 10.5330/ijpi.2019.4.29 · Published

    Background: Interleukin-10 is an important anti-inflammatory cytokine that plays significant roles in auto immune diseases. Interleukin-10 has been in- volved as an important regulator of the functions of myeloid cells l…

  2. Article

    Synthesis, Spectral Characterization and Biological Evaluation of Cr(III) Complex with Mixed N,N and O-donor Ligands

    R Govindharaju, N Muruganantham, S Balasubramaniyan, L Palanivelan, B Jayalakshmi, K Rajalakshmi, T Ramachandramoorthy

    pp. 158–163 · DOI: 10.5330/ijpi.2019.4.30 · Published

    Objectives: 2-aminobenzonitrile is used as the starting materials for the synthesis of many biologically active compounds. The main objective of the study was to synthesize, characterization and biological evaluation of …

  3. Article

    An Investigation through the Pharmacotechnical Factors-to Develop a Method to Replace a Super Disintegrant in an Immediate Release Tablet

    Dhanish Joseph, S.R. Suseem

    pp. 164–168 · DOI: 10.5330/ijpi.2019.4.31 · Published

    Objectives:The present work aim to identify the process parameters and technical parameters of granules that affect the disintegration time of an IR tablet. There by utilizing this knowledge to develop an IR tablet witho…

  4. Article

    Production and Optimization of Xylanase Enzyme from Bacillus subtilis using Agricultural Wastes by Solid State Fermentation

    Moorthy Marimuthu, Anbalagan Sorimuthu, Sankareswaran Muruganantham

    pp. 169–173 · DOI: 10.5330/ijpi.2019.4.32 · Published

    Background: Xylan, a major hemicellulosic polysaccharide found in the plant cell wall, represents up to 30-35% of the total dry weight of land plants. It is a heteropolysaccharide made up of a backbone of 1, 4-linked β-D…

  5. Article

    Preparation, Solid-State Characterization, Phase Solubility and Dissolution Studies of Azithromycin/Hydroxypropyl-β- Cyclodextrin Host-Guest System

    Mihir Raval, Hina Bagada

    pp. 174–179 · DOI: 10.5330/ijpi.2019.4.33 · Published

    Objectives:Azithromycin has poor aqueous solubility and its dissolution is the rate-limiting step. Therefore the objective of this work to increase the solubility and dissolution of azithromycin. Hence aim of the study w…

  6. Article

    Evaluation of Nootropic activity of Ethanolic and Aqueous Root Extracts of Adhatoda vasica nees in Rodents

    Kola Venu, Prasenjit Mondal, Rajesh BRC, Arjun Goje, Gummadevelly Sandeep, Manish Kumar Thimmaraju, Shaik Chanbasha, Bhookya Padmaja

    pp. 180–186 · DOI: 10.5330/ijpi.2019.4.34 · Published

    Objectives: The Present study was planned to evaluate the nootropic activ- ity of ehanolic extract of Adhatoda vasica nees (EERAV) and aqueous ex- tract of A. vasica (AQERAV) in experimentally induced amnesic models in m…

  7. Article

    Gastroprotective Effect of Acacia aroma Gill. ex Hook. and Arn. Leaves Extracts in Gastric Ulcer Models in Rats

    Felix Facundo Taboada, Natalia Cecilia Habib, Susana Beatriz Genta

    pp. 187–194 · DOI: 10.5330/ijpi.2019.4.35 · Published

    Background:Peptic ulcer is a disease caused by imbalance between pro- tective and aggressive factors in the gastric mucosa. Acacia aroma Gill. ex Hook. and Arn. (tusca) is widely used in Argentinian’s folk medicine for g…

  8. Article

    Antidiabetic Potential of Flavones on Streptozotocin-induced Diabetes Mellitus in Rat

    Binish Inam, Adil Inam, Monika Verma, Kamlesh Kumar Naik, Afroze Alam

    pp. 195–199 · DOI: 10.5330/ijpi.2019.4.36 · Published

    Objectives:The objective of the study was to develop new antidiabetic agents from synthetic route. Methods: An attempt was made to synthe- size various flavones. The structures of the compounds were elucidated by UV, IR,…

  9. Article

    Ameliorative Effect of Falcaria vulgaris on Nicotine-induced Injury on the Hippocampus Dentate Gyrus Region of Rats

    Shiva Roshankhah, Amir Abdolmaleki, Cyrus Jalili, Mohammad Reza Salahshoor

    pp. 200–204 · DOI: 10.5330/ijpi.2019.4.37 · Published

    Objectives: The dentate gyrus (DG) is a part of a brain region known as hippocampus. Falcaria vulgaris (FV) is a vegetable that contains antioxidant ingredients. Nicotine is one of the main risk factors in functional dis…

  10. Article

    Hypoglycemic, Antitussive and Analgesic Effects of Nanoparticles of Cordia myxa Fruits Extract

    Shokooh Salimimoghadam, Ali Ashrafi, Fakhri Kianidehkordi, Hossein Najafzadehvarzi

    pp. 205–209 · DOI: 10.5330/ijpi.2019.4.38 · Published

    Background:Cordia myxa is a plant from Boraginaceae family and has many useful therapeutic properties. Aim of the study is to compare the pharmacological efficacy of Cordia myxa hydro-alcoholic extract (Bulk Extract [BE]…

  11. Article

    Influence of Physical Activity Body Mass Index on Perceived Physical Self-Concept among Undergraduate Students of Saudi Arabia

    Varghese C Antony, Kaukab Azeem

    pp. 210–214 · DOI: 10.5330/ijpi.2019.4.39 · Published

    Background: Self-concept is one of the important aspect of our personal- ity. Physical self-concept defined as person’s perception of themselves in relation to his/her physical skills and outwards appearance. Objectives:…

  12. Article

    Knowledge, Attitude and Practice of Community Pharmacists on Medication Safety during Pregnancy: A Cross-sectional Study

    Goruntla Narayana, Payal Pandey, Alluri Gullakunta Ashok Kumar, Anil Kumar, Bhupalam Pradeepkumar, Kasturi Vishwanathasetty Veerabhadrappa

    pp. 215–219 · DOI: 10.5330/ijpi.2019.4.40 · Published

    Background: Safe medication use during pregnancy requires a great un- derstanding of the benefits and risks associated upon use of the drug. Community Pharmacists (CPs) are the most accessible health care pro- fessionals…

Short Communication

  1. Communication

    In silico Docking Studies and Potential Lead Identification against JNK3 for Alzheimer’s Disease

    Nishtha Singh, Sonal Upadhyay, Ankur Jaiswar, Nidhi Mishra

    pp. 220–222 · DOI: 10.5330/ijpi.2019.4.41 · Published

    Background: Alzheimer’s Disease (AD) is a neuron related brain disorder leading to reasoning and memory loss. There is no specific cure identified for AD. JNK3 (c-Jun N-terminal kinase /stress-activated protein kinase) a…