Volume 13, Issue 4

Lakshmi Prasanthi Nori, Sheik Rehana, Anusha Penamacha, Bhanu Mounika Somalanka, K. Venkateswara Raju

pp. 680–687 · DOI: 10.5530/ijpi.13.4.085 · 2023

The seriousness of presence of nitrosamines came to Limelight after USFDA and EMEA declared in July 2018 that N-Nitroso dimethylamine and N-N-NDMA are focused on the pharmaceutical medicinal products and particularly use…

Surya Nath Pandey, Payal Mittal, Gurfateh Singh

pp. 688–697 · DOI: 10.5530/ijpi.13.4.086 · 2023

The majority of millet is grown in Nigeria, Mali, Faso, Burkina, Chad, China and India. There are many different types of millet found throughout the universe, but finger millet, small millet, foxtail millet, and proso m…

Arjun HR, Praveen Halagali, Mohammed Tausif, Vaishnavi J, Rakshith U.R, GS Rakshanaa

pp. 698–702 · DOI: 10.5530/ijpi.13.4.087 · 2023

Diabetes type 3C is referred to as pancreatogenic diabetes also, which is occurring due to pancreatic cancer, pancreatitis, cystic fibrosis, and also pancreatic disease. In this condition, there is an inconsistent blow f…

Lakshmi Prasanthi Nori, Aditya Nidumolu, Terli Ragdeep, Vyasam Vishnu Vardhan, K. Venkateswara Raju

pp. 703–710 · DOI: 10.5530/ijpi.13.4.088 · 2023

A new class of biopharmaceuticals are developed by changing profile in terms of chemistry structure and functionality resulting in enhanced efficacy in terms of reduction in immunogenicity toxicity and improvement in hal…

Prasenjit Mondal, Saptarshi Samajdar, Suman Acharyya, Sumanta Mondal

pp. 711–720 · DOI: 10.5530/ijpi.13.4.089 · 2023

Alzheimer's disease is a progressive brain condition. It is characterized by alterations in the brain that result in the deposition of certain proteins. The brain shrinks and finally dies as a result of Alzheimer's disea…

Gandraju Akhila, Nagashree AG, Asha Spandana KM, Hemanth Kumar S, Harshith HS, Vishnu Vardh R, Shailesh T

pp. 721–734 · DOI: 10.5530/ijpi.13.4.090 · 2023

Cancer is one of the leading causes of death across the world, which is caused by tumours. Breast Cancer (BC) is the most common cancer in women and the second most common cancer death in women. A variety of molecular bi…

Nayeema Khowser Shaik, Nalluri Poojitha, Kancharla Bhanu Sri Chandana, Maruvajala Vidyavathi, Sai Deepthi Rayadurgam Venkata

pp. 735–746 · DOI: 10.5530/ijpi.13.4.091 · 2023

The highly infectious Corona Virus Disease 2019 (COVID-19) had spread and created a havoc worldwide due to lack of risk assessment and quick transmission. The outbreak created epicenters are still being reported daily. D…

N. Raghavendra Naveen, Keerthiraj KS, Gaganashree G, Prajitha Biju, Annegowda H V, Sindhoor S M

pp. 747–753 · DOI: 10.5530/ijpi.13.4.092 · 2023

The objective of the present was to formulate a novel topical P-herbo dosage form by incorporating the extracts of Azadirachta indica, Centella asiatica, and Ocimum gratissum and compare the efficacy. There is a strong c…

Krithiga Venkatesan, Gouranga Dutta, Damodharan Narayanaswamy, Abimanyu Sugumaran

pp. 754–762 · DOI: 10.5530/ijpi.13.4.093 · 2023

Introduction: SLNs have a surfactant-stabilized solid lipid core. They circumvent liquid lipid constraints and increase drug stability. Lipids promote oral medication absorption through the lymphatic pathway and replace …

Piyali Khamkat, Vivek Barik, Bhakti Bhusan Barik, Aritra Chakraborty, Dipsikha Patra, Prasenjit Mondal, Snigdha Chatterjee

pp. 763–771 · DOI: 10.5530/ijpi.13.4.094 · 2023

Background: To design and develop propranolol hydrochloride sustained-release tablet formulations using different grades of HPMC and MCC and their in vitro evaluations. The effect on drug release from tablets and other c…

Mythili Gopalakrishnan, Subramanian Somaskanthan

pp. 772–777 · DOI: 10.5530/ijpi.13.4.095 · 2023

Background: Capecitabine (CAP), a BCS class-I drug which is used for the treatment of Colorectal Cancer (CRC). Site specific and enzyme activated drug delivery was achieved by albumin coated nanoparticles. Co-administrat…

Fatemeh Zisti, Kethineni Chandrika, Davoud Balarak

pp. 778–783 · DOI: 10.5530/ijpi.13.4.096 · 2023

Background:Pharmaceutical residues are biologically active in trace concentrations. This has increased worries about their potential hazards to human health and living organisms and has highlighted the need to treat them…

Arshad Nehal Jamali, Rupesh Soni

pp. 784–788 · DOI: 10.5530/ijpi.13.4.097 · 2023

The study's objective was to evaluate Exenatide for treating Type 2 Diabetic Mellitus (T2DM) in an animal model. The safety profile and dose determination for the in vivo antidiabetic study were established through an ac…

Zouheir Ibrahim Bitar, Adnan M A Hajjiah, Ossama Sajeh Maadarani, Mahmoud Mostafa Elzoueiry, Mohamed Refaat Gohar, Mohamad Abdelfatah, Fawaz Alabdali

pp. 789–792 · DOI: 10.5530/ijpi.13.4.098 · 2023

Introduction: The reported hypocalcemia was low in denosumab-treated postmenopausal women with osteoporosis (0.05–1.7% to 7.4%). The major prediction factors were Vitamin D and calcium levels and renal function. Aim:To a…

Sirisha Kalyani Bandi, Prasunpriya Nayak, Kalyani Mallipeddi, Archana Rajagopalan

pp. 793–797 · DOI: 10.5530/ijpi.13.4.099 · 2023

Background:The brain is highly susceptible to Aluminium’s (Al) toxic impact due to its elevated lipid content and oxygen utilization but, relatively scanty levels of antioxidants. Al is known for its strong pro-oxidant a…

Meriga Pramod Kumar, S. Afreen, M. Kalpana, T. Sailaja, M. Venkatesh Naik, M Sureshwara Reddy

pp. 798–804 · DOI: 10.5530/ijpi.13.4.100 · 2023

Background:As many pharmaceuticals are removed via the kidneys, a dose adjustment for some medications is necessary in individuals with decreased renal function to prevent toxicity. This study aimed to modify the dose in…

Chaithra Raviraj, Chakrakodi Shashidhara Shastry, Anish John, Harsha Ashtekar

pp. 805–811 · DOI: 10.5530/ijpi.13.4.101 · 2023

Aim:To identify native plant species with high tolerance and remediation potential for specific pollutants present in the industrial area, aiming to develop effective and sustainable phytoremediation strategies for envir…

Dhanabalan Rangasamy, Dhiviya Jeyarajan, Lavanya Gunasekaran

pp. 812–816 · DOI: 10.5530/ijpi.13.4.102 · 2023

Background:The present study has been carried out to explore antifungal property of folklore medicinal herbs Solanum trilobatum, Spathodea campanulata, Syzygium jambos and Tylophora indica prevalent among the tribal comm…

Shilpa P. Chaudhari, Priyatama Vijaysing Powar

pp. 817–827 · DOI: 10.5530/ijpi.13.4.103 · 2023

Phyllanthus acidus (L.), a medicinal plant, shows numerous pharmacological properties like antioxidant, anti-inflammatory, hypoglycemic effects, neuroprotective, anti-diarrheal, anti-pyretic, and analgesic and anaestheti…

Rakshita Pawar, Athira Sasidharan, Manohar Kumar, Yogish Somayaji, Ronald Fernandes

pp. 828–836 · DOI: 10.5530/ijpi.13.4.104 · 2023

Background: Neuroprotection is a process of recovery and salvage of the nervous system, function, and structure of cells. Several modulators are leading to neuronal damage and cell death, causing many neurodegenerative d…