Volume 14, Issue 2

Supriya Bhukya, Sonam Swain, Darna Mounika, Jyoti Honnanayakanavar, Battu Harish, Purna Chandra Behera, Vidya Jyothi Alli, Surender Singh Jadav, Anthony Addlagatta, Surisetti Suresh, Nishant Jain

pp. 436–453 · DOI: 10.5530/ijpi.14.2.54 · 2024

Background Antimicrotubule agents effectively block cancer spread and are routinely employed as front-line chemotherapeutics. But patients, who receive Paclitaxel, suffer from peripheral neuropathy, which not only lowers…

Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Vishwanath Swamy, Amisha Netalakar, S K Bhoomika, D Namratha, Tahameen K Kurabanavar

pp. 454–461 · DOI: 10.5530/ijpi.14.2.55 · 2024

Background Cardiovascular Disease (CVD) commonly known as disease of heart blood vessels and is typically composed of fatty deposits. The WHO estimates that approximately 17.3 million people worldwide die each year from …

Muhammad Abid Mustafa, Asad Majeed Khan, Minahil Arif, Nahan Khan, Namra Rasheed, Muhammad Abuzar Ghaffari, Nabeela Jabeen, Areej Faisal, Aneeqa Zia, Abdullah Saleem, Kaynat Azar, Sheeza Khaliq, Hassan Yasin, Ayesha Zulfiqar

pp. 462–471 · DOI: 10.5530/ijpi.14.2.56 · 2024

Background Mucoadhesive buccal tablets are well established, widely used, and commonly accepted oral dosage forms that, by virtue of their adhesiveness, allow the drug to be released gradually over an extended period. Va…

Bhageerathy Anantha Narayana Iyer, Prasanth Viswanadhan Vasantha

pp. 472–481 · DOI: 10.5530/ijpi.14.2.57 · 2024

Purpose The study aimed to formulate and evaluate an ocular effective prolonged release cubogel formulation of Moxifloxacin Hydrochloride (MX-Cubogel) to treat conjunctivitis. Materials and Methods Initially, a Moxifloxa…

K Sreena, Meenu C Nair, S Ghanthi Kumar, B Neethu Kannan, V L Reena, Sreenidhi M Varma, G S Lekha

pp. 482–492 · DOI: 10.5530/ijpi.14.2.58 · 2024

Background The present study deals with the detailed pharmacognostic investigation of Sidhha single drug, the stem of Cissus vitiginea L. It is a climber that belongs to the family ‘Vitaceae’ with a pantropical distribut…

Anju James, Praveen Halagali, M Jafar, Jose Sanu, Rajath K Bharadwaj, Benwin Shaju, Sahal Basheer, Hunsur Ranganath Arjun, Preethi Somanna

pp. 493–503 · DOI: 10.5530/ijpi.14.2.59 · 2024

Background Fumaria parviflora (FP) is a medicinal herb that is used in several traditional medicines to treat diseases like folliculitis, erysipelas. Fumaria parviflora Lam. belonging to the family Papaveraceae is used w…

Chandrashekar Ranga, Tanveer Naved, Arti Thakkar

pp. 504–508 · DOI: 10.5530/ijpi.14.2.60 · 2024

Background The need of developing a vaccine on emergency basis to COVID-19 has captured the attention of the regulator during the recent pandemic. There is no comprehensive regulatory pathway for the development of a nov…

Chrishelle Jaculin, Dhivya Viswanathan, Rajakumar Govindasamy

pp. 509–516 · DOI: 10.5530/ijpi.14.2.61 · 2024

Background This study investigated the biosynthesis of Copper Oxide Nanoparticles (CuONPs) using an environmentally safe and sustainable approach based on Amaranthus tricolor extract. Materials and Methods The synthesize…

Venkata Naga Jyothi Nakka, Kumar Shiva Gubbiyappa

pp. 517–524 · DOI: 10.5530/ijpi.14.2.62 · 2024

Background The bioavailability of the drug is influenced by the solubility of the drug in the biological fluids. Solubility and dissolution are the rate-limiting steps for the absorption and bioavailability of BCS class …

Sudhanshu Shukla, Neeraj Hiremath, Arnab Sarkar, Atharv Mirajkar, Jayasheela Siddhalingayya Hiremath, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Vishwanatha Swamy

pp. 525–530 · DOI: 10.5530/ijpi.14.2.63 · 2024

Background Hypertension is a chronic long-stay disease that requires proper treatment management and regular medication assessment, which ensure that the disease does not progress into a disorder. Medication Adherence is…

T Mallamma, Pradeep B. Mirje, Somanagouda Patil, Jayatheertha S. Lokapur, Arpitha J. Lokapur

pp. 531–538 · DOI: 10.5530/ijpi.14.2.64 · 2024

Background Wound healing is a complex physiological process that involves a cascade of events, from inflammation to tissue remodeling. Impaired wound healing can lead to chronic wounds, which are painful and susceptible …

Vinuth Chikkamath, Venkatrao Kulkarni, Prasanna Habbu, Anantha Naik Nagappa

pp. 539–546 · DOI: 10.5530/ijpi.14.2.65 · 2024

Background The Advent of the COVID -19 pandemic has necessitated the quick exploration of new drugs. Synthetic approach is time consuming and expensive with uncertainty. The natural products can be explored as this appro…

Chintha Madhavi, Guntakanti Ujwala, Shaik Shahinshavali, Thammineni Jithendra, Obireddy Sreekanth Reddy

pp. 547–553 · DOI: 10.5530/ijpi.14.2.66 · 2024

Background Magnetic nanoparticles are valued in medical applications for their distinctive properties. In this study, we synthesized magnetic nanoparticles with the aim of employing them for drug delivery. Materials and …

Moubonny Das, Pinaki Biswas, Somasri Dam

pp. 554–567 · DOI: 10.5530/ijpi.14.2.67 · 2024

Background Amoebiasis, caused by the human pathogen Entamoeba histolytica is one of the most common parasitic diseases. The existing anti-amoebic drugs show significant side effects in humans. Therefore, for effective co…

H S Mythri, Krishnan R Nithin, Raja Ram Mahto, Anil Kumar

pp. 568–576 · DOI: 10.5530/ijpi.14.2.68 · 2024

Background With a high incidence and prevalence of Diabetes and an increase in population of elderly, reports project the number of diagnosed diabetes cases among people 65 years and older will grow more than 4-fold from…

Mahesh Hari Kolhe, Sameer Narayan Godase, Kavita Bhushan Vikhe, Rohit Jaysing Bhor

pp. 577–584 · DOI: 10.5530/ijpi.14.2.69 · 2024

Objectives To develop and validate a sensitive, accurate, simple, precise and cost-effective UHPLC method for the simultaneous determination of Teneligliptin and Pioglitazone in pure and its tablet formulation form and v…

Sameer Narayan Godase, Kavita Bhushan Vikhe, Mahesh Hari Kolhe, Shubham Balasaheb Mhaske, Rohit Jaysing Bhor, Payal Sopan Gawali

pp. 585–592 · DOI: 10.5530/ijpi.14.2.70 · 2024

Background Teneligliptin is a new drug recently approved by FDA for treatment of type 2 Diabetes Mellitus (DMT 2). Very few methods have been reported for analysing its degradation products and their impact on human heal…

Ravinandan Adavappa Parvathamma, Eswaran Maheswari

pp. 593–594 · DOI: 10.5530/ijpi.14.2.71 · 2024