Volume 14, Issue 3

Akram Ahmed Aloqbi

pp. 595–606 · DOI: 10.5530/ijpi.14.3.72 · 2024

This review provides an extensive summary of the most current expansions on the therapeutic potential of ginger bioactive compounds in the context of cancer management. We delve into the individual components of ginger a…

Pratheksha Suresh, Vivek Reddy Murthannagari, Ganesh Gonna Nandhi Krishnan, Neerej Shivashankar, Tholkapiyan Mullaiventhan

pp. 607–615 · DOI: 10.5530/ijpi.14.3.73 · 2024

Historically, there have been constraints on pediatric drug trials, resulting in an absence of authorized medicines for children and a significant reliance on off-label use. Pediatric drug development is critical to addr…

Prachi Pandey, Rahul Pal, Vinay Kumar Rao Khadam, Himmat Singh Chawra, Ravindra Pal Singh

pp. 616–632 · DOI: 10.5530/ijpi.14.3.74 · 2024

Targeted drug delivery systems are employed to administer pharmaceutical medication, facilitating the precise delivery of drugs to specific diseased areas. Several drug delivery systems utilise carriers such as antibodie…

Koushik Narayan Sarma, Chandrashekar Thalluri, Jithendar Reddy Mandhadi

pp. 633–646 · DOI: 10.5530/ijpi.14.3.75 · 2024

Pharmaceutical formulations, polymer-based nanofibers, which have higher surface area per unit mass of solid, enable and contribute to functions linked to surface shape. Nanofibers can be made using a number of different…

Fatmah Alsharif

pp. 647–656 · DOI: 10.5530/ijpi.14.3.76 · 2024

This review article explores the transformative impact of Artificial Intelligence (AI) and Machine Learning (ML) in cancer research. It focuses on the critical role of AI in medical imaging for cancer detection, explorin…

Gaurav Tiwari, Sagar Narendra Ande, Varsha Deva, Nayyar Parvez, Mahesh Kumar Posa, Saumya Singh, Ruchi Tiwari

pp. 657–669 · DOI: 10.5530/ijpi.14.3.77 · 2024

All patients with Chronic Obstructive Pulmonary Disease (COPD), a multifactorial illness, have decreased post-bronchodilator lung function. While it was once believed that hyperresponsiveness and acute bronchodilator rev…

K H Harish, Agadi Hiremath Viswanatha Swamy

pp. 670–680 · DOI: 10.5530/ijpi.14.3.78 · 2024

Agmatine, an endogenous amine with cationic properties, serves as a precursor for polyamine synthesis and has diverse pharmacological effects on the central nervous system. Its neuroprotective mechanisms include preventi…

Umashankar Chikkanna, M Balakeshawa Ramaiah, Shanmuganathan Seetharaman, Vijayan Venugopal, Anandakirouchenane Elumalai, Chandrakala Venkatesh, Gururaj Giligarr

pp. 681–695 · DOI: 10.5530/ijpi.14.3.79 · 2024

This thorough analysis of the article describes the therapeutic potential of herbal treatments, such as ginger, papaya, bamboo shoots, and Plectranthus species, in addressing the complex issues of oxidative stress, micro…

Manish Kumar Gautam, Pritish Kumar Panda, Anubhav Dubey, Mamta Kumari, Niladry Sekhar Ghosh

pp. 696–701 · DOI: 10.5530/ijpi.14.3.80 · 2024

Background Zebrafish have emerged as an invaluable asset in biomedical research, particularly in comparison to other vertebrate models employed for studying human ailments. Their efficacy in large-scale studies of geneti…

K Swathi Priya, Veda Priya Gummadi, Gana Manjusha Kondepudi

pp. 702–711 · DOI: 10.5530/ijpi.14.3.81 · 2024

Objectives This study aims to assess the potential antidiabetic properties of aqueous extracts derived from the peels of specific fruits, including A.squamosa, C. melo, A. deliciosa and M. pumila. Materials and Methods M…

Basavaraj Dinnimath, Mahesh Palled, Shradha Sutar, Shradha Tashildar, Utkarsh Chavan, Sampada Ganpule

pp. 712–737 · DOI: 10.5530/ijpi.14.3.82 · 2024

Organometallic compounds are gaining prominence today as they are found to be potent anticancer agents due to their diverse chemical nature along with the metal with which they are chelated. In these organometallic compo…

Lakshmi Usha Ayalasomayajula, Chandra Sekhar Patro, Saroj Kumar Raul

pp. 738–748 · DOI: 10.5530/ijpi.14.3.83 · 2024

Background The present work covers the preparation and investigation of Nanoemulsion (NE) based hydrogel i.e., Nanoemulgel (NEG) of an Antifungal drug Oxiconazole delivered topically. Materials and Methods High-speed hom…

Prashant Halagali, Vishal I Wannur, Abishek Kumar A Patil, Vaibhavi D. Torgal, Shrikrishna M Naik, Santosh A Marennavar, Sakshi Shahapurmath, Pankaj Patil

pp. 749–758 · DOI: 10.5530/ijpi.14.3.84 · 2024

Introduction Ethosomes are non-invasive drug delivery systems that enable drugs to enter the bloodstream or deep layers of the skin and these are phospholipid-based elastic Nano vesicles with a high ethanol concentration…

Suvarna Sanjay Khairnar, Mohammed Saad, Jubershaha Salimshaha Fakir, Yogesh Suresh Ahire, Ziyaurrahman Ataurrahman, Nayana Kailas Patil

pp. 759–767 · DOI: 10.5530/ijpi.14.3.85 · 2024

Aim/Background Alcohol-induced liver necrosis requires effective treatment. This study tests Polyherbal Extract’s hepatoprotective effects on alcohol-induced liver necrosis in rats. The extract’s impact on inflammatory p…

Parag Patgiri, Biru Goyary, Mritunjoy Kumar Roy, Ananta Swargiary, Nisha Rani Brahma, Bihung Brahma

pp. 768–774 · DOI: 10.5530/ijpi.14.3.86 · 2024

Background Resistance to insecticides is one of the major problems in successfully controlling of mosquito-borne diseases. The present study explores the role of Voltage-Gated Sodium Channel (VGSC) and their mutation in …

Sandeep S Sagare, Ashok Patil, B S Prasad, S Kadambari

pp. 775–785 · DOI: 10.5530/ijpi.14.3.87 · 2024

Background Ayurveda, an ancient holistic health system, underscores personalized well-being through tailored approaches to health and disease. The post Vamana-Virechana procedures are vital in Ayurvedic detox, promoting …

Naveena Katta, Ashwini Madhava, Preethi Sudheer

pp. 786–793 · DOI: 10.5530/ijpi.14.3.88 · 2024

Background This study aimed to develop an efficient drug delivery system targeting the colon to treat inflammatory conditions using mesalamine. The approach involved formulating microsponges with Eudragit polymers, focus…

Shaffi Khurana Tangri, G gnanarajan, Vaibhav Sisodiya, Himanshu Rana, Mehak Garg, Pranshu Tangri, Vaishali Pathania

pp. 794–805 · DOI: 10.5530/ijpi.14.3.89 · 2024

Background This study’s objective was to create and assess diacerein-loaded microsponges incorporated into a topical gel formulation for enhanced skin delivery. Diacerein is a potent anti-inflammatory agent used in the m…

Dipti Gohil, Dixit Patel, Nirmal Shah, Chintan Aundhia, Sunil Kardani, Rahul Trivedi

pp. 806–813 · DOI: 10.5530/ijpi.14.3.90 · 2024

Background Topical alpha agonists approved by the FDA are used to treat rosacea. Because of its potent vasoconstrictor properties, brimonidine tartrate topical gel (0.33%) efficiently reduces erythema. The aim of this in…

Sunanda Thakur, Putta Venkata Nagendra Kumar, Kamal Shah, Medari Ravinder, Subhash Bhima Pawar, Byalla Sadasivaiah, P Shivakumar Singh, Nagendra Singh Chauhan

pp. 814–821 · DOI: 10.5530/ijpi.14.3.91 · 2024

Background Bio formation of the silver nanoparticles are eco-friendly, low cost, within short period could synthesised and widespread significances also performances. Objectives Seldom, the creation of extra-cellular sil…