Volume 14, Issue 4

Abdulaziz Mohammed Asiri, Amer Ali Ahmad Al, Maryam Musleh Althobiti, Mohammed Haidar Abu-Alghayth

pp. 983–997 · DOI: 10.5530/ijpi.14.4.108 · 2024

Background Cancer stands as a significant global health concern, leading to considerable patient suffering and death. The prognosis of patients is intricately connected to the metastatic extent of the disease to aloof si…

Gaurav Tiwari, Santosh Karajgi, Vattakkalvalasu Ramathan Ravikkumar, Ram Kumar Choudhary, Jegannathan Kannan Shyamala, Vinod Kumar, Sreenivas Pippalla

pp. 998–1009 · DOI: 10.5530/ijpi.14.4.109 · 2024

Colloidosomes, pioneering microcapsules composed of coagulated colloidal particles assembled at the interface of emulsion droplets, have garnered significant attention due to their remarkable properties and potential app…

Piyush Yadav, M Sreelakshmi, Vikas Chauhan, Ritu Mishra

pp. 1010–1018 · DOI: 10.5530/ijpi.14.4.110 · 2024

Precision medicine is an approach to provide individualized treatment to the patient for a specific disease based on the genotypic, phenotypic and also psychological factors which in turn enhances the patient care to sev…

M Keerthana, DS Sandeep, T Shailesh, KM Asha Spandana, S Kathirvel, HK Pradeep

pp. 1019–1024 · DOI: 10.5530/ijpi.14.4.111 · 2024

FDA has implemented 21 CFR 111 guidelines to regulate the production of dietary supplements that are sold in dosage forms. Creating an effective quality system demands both time and financial resources. However, the robu…

Prajwal Chamanahalli Balaraju, Jayanth Baburayanakoppal Manchegowda, Chandan Kumar, Bharathi Doddla Raghunathanaidu, Ananth Gowda K M Doddi Hanumaiah, Varun Nagamangala Lokesha, Syed Sagheer Ahmed

pp. 1025–1034 · DOI: 10.5530/ijpi.14.4.112 · 2024

In the realm of healthcare, Central Nervous System disorders pose a formidable challenge, affecting countless lives globally. Conditions like Alzheimer’s, Parkinson’s and traumatic brain injuries exact a heavy toll. Howe…

Pawan Kumar Gupta, Yogendra Pal, Prashant Kumar, Shweta Gupta, Shiv Dev Singh, Shashi Bhooshan Tiwari

pp. 1035–1041 · DOI: 10.5530/ijpi.14.4.113 · 2024

Advancements in computational techniques have revolutionized the field of drug design, offering a powerful arsenal of tools collectively known as in silico methods. This review provides an overview of the diverse computa…

Mujibullah Sheikh, Saniya Makkad, Sanskruti Shende, Mrunal Deshmukh

pp. 1042–1051 · DOI: 10.5530/ijpi.14.4.114 · 2024

Titanium dioxide nanoparticles, or TiO2 NPs, have shown potential in the fight against a range of diseases, including bacteria, viruses, fungi and parasites. Doping metals with nanoparticles modify their size and magneti…

Akanksha Porwal, A Rajendiran, Parwz Alam, Himanshu Singh, Kratika Singh, Ayush Dubey

pp. 1052–1060 · DOI: 10.5530/ijpi.14.4.115 · 2024

The indole moiety, a prevalent and versatile heterocyclic scaffold, plays a pivotal role in the realm of organic synthesis, underpinning the structural basis of myriad natural products, pharmaceuticals and advanced mater…

Harlin Swer, Bharat Rathi, Anita Wanjari, Payal Raut, Aditi Shinde, Manasi Chunchuwar, Anjali Katore

pp. 1061–1068 · DOI: 10.5530/ijpi.14.4.116 · 2024

Background Psoralea cordifolia Linn. is also known as Bakuchi in Sanskrit and is found all over India. It has long been known for its therapeutic benefits and use in a variety of ailments. This plant belongs to the Fabac…

Maged Mohammed Abdo Mohsen, Amit B Patil, Manohar Sidramayya Kalhandaki, Deepak Kumar Jha, Sangram Ambalgikar

pp. 1069–1078 · DOI: 10.5530/ijpi.14.4.117 · 2024

Today’s drugs, not all usually soluble and easy to formulate drug actives, they might be potent drug molecules at their specific target, they can never become a successful therapy, or molecule, or product if they are not…

Sindoora Dabbe Seetharama, Akalu Srinivas Kamakshi Shriya, Vaishnavi Bharat Pawar, Balaji Sathyanarayana Gupta, Shilpa Palaksha

pp. 1079–1084 · DOI: 10.5530/ijpi.14.4.118 · 2024

Medication adherence has always been an integral aspect to achieve any healthcare benefit of pharmacological treatment. Although health care has evolved remarkably, the need for conducting studies on medication adherence…

Siva Prasad Sunkara, Nihar Ranjan Kar, Shaik Kareemulla, Koushik Narayan Sarma, Komal Umare Thool, Manoj Kumar Katual, Pydiraju Kondrapu

pp. 1085–1095 · DOI: 10.5530/ijpi.14.4.119 · 2024

Exosomes are small nanovesicles that are produced through the fusion of multiple veins and plasma membranes, then escaping into adjacent body fluids. Considerable attention has been paid to them due to their potential as…

Abdulrahman Alzahrani

pp. 1096–1114 · DOI: 10.5530/ijpi.14.4.120 · 2024

The ongoing COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has spurred unprecedented research efforts worldwide. This comprehensive scientific review synthesizes key research developments and understandin…

Chitrashree Mahadeviah, Purushotham Karadigere Nagaraj, Thoppalada Yunus Pasha, Priyanka Marathi

pp. 1115–1121 · DOI: 10.5530/ijpi.14.4.121 · 2024

The core structure is an aromatic heterocyclic organic compound i.e. Isoquinoline. Both the structures of Isoquinoline and quinoline contain a fused ring structure of benzene and pyridine. Isoquinoline, the pyridine coun…

Cynthia Lizzie Lobo, Pavithra Pradeep Prabhu, Akhilesh Dubey, Amitha Shetty, Manohar Mahadev

pp. 1122–1130 · DOI: 10.5530/ijpi.14.4.122 · 2024

Hesperidin, a natural compound abundant in citrus fruits, shows promise in breast cancer management due to its safety and diverse mechanisms of action. This review explores hesperidin’s origin, chemical properties, and i…

Poonam Dada Waditake, Mahesh Hari Kolhe, Mayuri Kailas Mate, Rohit Jaysing Bhor, Pratibha Sudhakar Bhalerao, Manjusha Pandharinath Mhaske

pp. 1131–1137 · DOI: 10.5530/ijpi.14.4.123 · 2024

Background Remogliflozin etabonate belongs to the gliflozin class used for the treatment of type 2 diabetes mellitus and non-alcoholic steatohepatitis. Objectives The objective of the present study is to develop an accur…

Madhan Kumar Srinivasan, Lalitha Vaidyanathan, Juwala Malinika, Sangeetha Chellapandi

pp. 1138–1146 · DOI: 10.5530/ijpi.14.4.124 · 2024

Background One of the etiologies of stroke is intracerebral hemorrhage and the demand for potential therapeutic agents to alleviate symptoms and improve quality of life in patients with ICH is growing. Several phytocompo…

Bommaiah Prakash Kumar, T Yunus Pasha

pp. 1147–1154 · DOI: 10.5530/ijpi.14.4.125 · 2024

Aim The proposed study was to establish a Greener method and validation, by green chromatography technique for combined anti-viral drugs, measuring greenness using various tools, which is one of the emerging developments…

Sharada Laxman Deore, Bhushan Arun Baviskar, Shretali Sawarkar, Shraddha Bhalake, Anjali Kide, Bhavana Shende, Ram Vighne

pp. 1155–1165 · DOI: 10.5530/ijpi.14.4.126 · 2024

Background Berberine, a phytochemical, possesses remarkable potential for multitargeted drug therapy in microbial infections, wound healing and anti-inflammatory applications. However, its clinical utility in skin and ot…

Vankodoth Sireesha, Yapachetty Pravarsha, Sumaya, Kompalli Varun, N. Chaitanya, CH Meghana, K. Megana

pp. 1166–1173 · DOI: 10.5530/ijpi.14.4.127 · 2024

Background Ascites is the accumulation of abdominal fluid in the peritoneal cavity. Liver cirrhosis, Alcoholic liver disease, Intra-abdominal malignancy, and tuberculosis are the significant etiologies of ascites. In our…