International Journal of Pharmaceutical Investigation
Volume 15, Issue 3
2025 · pp. 675–1061 · 43 articles
- Volume
- 15
- Issue
- 3
- Published
- 2025
- Pages
- 675–1061
- Articles
- 43
- Sections
- 4
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
21–40 of 43Original Article(continued)
- Article
Prerana Badrinath Jadhav, Shital Vilas Wagh, Manjushri Pratap Dabhade
pp. 873–887 · DOI: 10.5530/ijpi.20250157 · 2025
Background The need for new antibacterial medicines arises from the emergence of antibiotic-resistant bacterial strains. Pyranopyrazole derivatives, known for their diverse biological activities, are investigated for the…
- Article
Naveen Kumar Mohan, Muneeswari Kumar, Amudhanila Padmanaban, Farhanaaz, Zakirullah Samad, Abdul Jaffar Ali Hajamohideen
pp. 888–894 · DOI: 10.5530/ijpi.20250177 · 2025
Background Antibiotic-resistant bacteria pose a significant threat to public health, leading to the development of novel therapeutic approaches. Staphylococcus aureus, a common pathogenic microbe, is a major global healt…
- Article
Satti Sandeep Reddy, Rajendran Vijayalakshmi, Shaik Sadhik Ansari, Pilli Sandya
pp. 895–902 · DOI: 10.5530/ijpi.20250183 · 2025
Objectives To quickly and easily identify and quantify Mirabegron and Silodosin in both pure and pharmaceutical dosage forms, a gradient Reverse-Phase High Performance Liquid Chromatography (RP-HPLC) technique was descri…
- Article
Ramesh Bhandari, Madiwalayya Shivkantayya Ganachari
pp. 903–908 · DOI: 10.5530/ijpi.20250187 · 2025
Objectives To evaluate Health-Related Quality of Life (HRQoL) and its determinants among dyslipidemia patients. Materials and Methods A cross-sectional study was conducted among patients with dyslipidemia during 6 months…
- Article
Tejas Vyas, Ujashkumar Shah, Jayvadan Patel, Mrityunjay Tiwari
pp. 909–916 · DOI: 10.5530/ijpi.20250223 · 2025
Background Water-soluble B-complex vitamins are essential for energy metabolism and overall health. Objectives To develop a simple, sensitive, accurate, validated and cost-effective reverse phase liquid chromatographic m…
- Article
Suresh Ramasamy, Senthamil Selvi Gopalan, Kiruba Annammal Paul Abraham Antonyraj, Siva Annamalai, Abarna Balasubramani, Natarajan Mohan, Sanjana Subramaniam
pp. 917–925 · DOI: 10.5530/ijpi.20250260 · 2025
Background The Siddha system, widely practiced in Tamil Nadu, incorporates plant, mineral and animal components in its medicinal formulations. Vaalai Rasa Mezhugu (VRM) is one such herbo-mineral preparation indicated for…
- Article
Rakesh Meher, Roja Sahu, Santosh Kumar Ranajit, Trupti Rekha Swain, Rabinarayan Rana, Prafulla Kumar Sahu
pp. 926–932 · DOI: 10.5530/ijpi.20250235 · 2025
Introduction Polypharmacy, use of narrow therapeutic index drugs and clinical co-morbidities make the patients administered with psychotropics vulnerable to Adverse Drug Reactions (ADRs) and hence, awareness about it is …
- Article
Lakshmi Priya Bachina, Anusha Kanagala
pp. 933–941 · DOI: 10.5530/ijpi.20250107 · 2025
AI technologies affect consumers' attitudes, perceived risk and levels of trust, which in turn affects their purchase behavior. The study explores how AI tools, such as voice search, chatbots and recommendation systems, …
- Article
Essakki Subbulakshmi, Sudalaiyanminudi Kumaresan, Pandaram Palanisamy
pp. 942–952 · DOI: 10.5530/ijpi.20250195 · 2025
Background This study explores the phytochemical composition, molecular interactions and cytotoxic potential of ethanolic extracts from four medicinal plants-Solanum virginianum, Hibiscus rosa-sinensis, Piper betle and E…
- Article
Neelima Danga, Rama Devi Korni, Vasavi Laveti, Karakavalasa SVVS Sai Sampath, Jagadeesh Panda, Pavan Kumar Pinagadi
pp. 953–960 · DOI: 10.5530/ijpi.20250172 · 2025
Background Serotonin Reuptake Inhibitors (SSRIs) like paroxetine are selective. It is used to treat several illnesses, such as premenstrual dysphoric disorder, post-traumatic stress disorder, obsessive-compulsive disorde…
- Article
Anita Dattatray Kadam, Dipali Manoj Khopade, Suresh Bubu Kondaveeti, Hitender Singh Batra
pp. 961–965 · DOI: 10.5530/ijpi.20250124 · 2025
Background Leprosy, an ancient Disease remains a notable health concern in certain nations like India. It is an ongoing disease of infection brought on by Mycobacterium leprae. The production of Nitric Oxide by the actio…
- Article
Lakshmi Thabaj, Rashmi Surve, Shweta Myagadeyavar, Udaykumar Bolmal
pp. 966–971 · DOI: 10.5530/ijpi.20250226 · 2025
Background This study aimed to formulate and evaluate a sunscreen gel containing Morinda citrifolia (Noni) fruit extract, focusing on its Sun Protection Factor (SPF). Sunscreens are primarily used for photo protection an…
- Article
Mandati Santhosh Reddy, Pratiksha Nagesh Kini, Madiwalayya Shivkantayya Ganachari
pp. 972–976 · DOI: 10.5530/ijpi.20250180 · 2025
Introduction Adverse Drug Reactions (ADRs) present major challenges in healthcare, contributing significantly to hospital admissions and impacting a large number of inpatients. Monitoring ADRs often relies on electronic …
- Article
Rajendran Vijayalakshmi, Shaik Sadhik Ansari, Satti Sandeep Reddy, Pilli Sandya
pp. 977–983 · DOI: 10.5530/ijpi.20250222 · 2025
Background This study work introduces a straightforward, sensitive, specific, and efficient stability-indicating HPLC approach designed for the simultaneous measurement of Almitrine and Raubasine in both pre-formulation …
- Article
Bachunaga Kishore Babu, Daniel Pilli, Podile Venkateswara Rao, Veena Tewari
pp. 984–991 · DOI: 10.5530/ijpi.20250247 · 2025
Background The pharmaceutical industry faces ongoing challenges in mass production, drug personalization, and sustainable packaging. Traditional manufacturing methods often fail to meet the growing demand for tailored th…
- Article
Rashmitha Rama Devadiga, Sadeeksha, Reeha, Rohan, Ashwini Madhava
pp. 992–997 · DOI: 10.5530/ijpi.20250191 · 2025
Background Skincare products featuring natural ingredients are widely favored for their perceived efficacy and safety. This study aimed to develop and evaluate cocoa fruit-based formulations for skincare, enriched with s…
- Article
Optimization and Validation for Simultaneous Estimation of Metformin and Furosemide by Using RP-UFLC
Rakshitha Anjaneya, Rashmi Neligare Gopala
pp. 998–1005 · DOI: 10.5530/ijpi.20250046 · 2025
Background Metformin is a Biguanide derivative used to treat the type-II diabetes, Furosemide is a loop diuretic used in the treatment of hypertension associated with edema. Aim: Our aim is to create an analytical method…
- Article
Assessment of the Anti-Tubercular Efficacy of a Hybrid Compound Using in vitro and in silico Methods
Akula Sowjanya, Joshi Meripe, Midde Jeevitha, Udutha Bhanu Prasad, Mallika Shaik, Maipala Uma Mahesh
pp. 1012–1016 · DOI: 10.5530/ijpi.20250132 · 2025
Background Tuberculosis is mostly caused by Mycobacterium tuberculosis; however, it can be caused by a variety of mycobacteria. Tuberculosis predominantly impacts the respiratory system, although it may also affect other…
- Article
Smrutiranjan Dash, Rajasekaran Sidhan
pp. 1017–1038 · DOI: 10.5530/ijpi.20250283 · 2025
Background Herbal medicines have been valued for centuries as potent treatments for various conditions, including inflammatory and microbial infections. Urochloa distachya (Signal grass), an annual grass belonging to the…
- Article
Rohit Gawali, Rahul Keshav Godge, Kavita Dhamak, Arshu Patel
pp. 1039–1044 · DOI: 10.5530/ijpi.20250328 · 2025
Aim A Rational and time-efficient, as well as, selective and gentle approach based on simultaneous estimation to the RP-HPLC verification in compliance with the most recent requirements for nirmatrelvir and ritonavir. Ma…