International Journal of Pharmaceutical Investigation volume 15, issue 4 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 15, Issue 4

2025 · pp. 1–1424 · 41 articles

Volume
15
Issue
4
Published
2025
Pages
1–1424
Articles
41
Sections
2
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI

In this issue

1–20 of 41

Original Article

  1. Article

    Arvind Raghav, Vaibhav Rastogi, Arulsamy Elphine Prabahar

    pp. 1–7 · DOI: 10.5530/ijpi.20250308 · 2025

    Background An easy, quick, sensitive and precise extractive spectroscopic approach has been devised for the determination of lauric acid in pure form as well as present in virgin coconut oil. The approach is based on the…

  2. Article

    Vandhana Vijayakumar, Thirumalaikumaran Rathinam, Abida Haripriya Rammohan, Dharshini Sagadevan, Udhayakumar Thangavelu

    pp. 1168–1174 · DOI: 10.5530/ijpi.20250175 · 2025

    Objectives This study centers on the development and assessment of a facial serum fortified with the innate antioxidant’s resveratrol and quercetin, to address skin aging and acne. Materials and Methods The serum was car…

  3. Article

    Harshitha Nagaraj, Kusu Susan Cyriac, Deepak Kumar Jha

    pp. 1175–1183 · DOI: 10.5530/ijpi.20250149 · 2025

    Background Inflammation is the body's innate defence mechanism that is initiated in reaction to injury or on exposure to detrimental agents. Plumeria alba Linn, a small laticiferous tree rich in phytochemicals and antiox…

  4. Article

    Amaresh Chandra Sahoo, Sujit Dash, Prabhat Kumar Sahoo, Minaketan Sahoo

    pp. 1184–1194 · DOI: 10.5530/ijpi.20250206 · 2025

    Background Emulgel is a combination of gel and emulsion. Drugs are first incorporated into an emulsion and then the conventional emulsion is transferred into an emulgel by using a gelling agent. Objectives To formulate a…

  5. Article

    Ang Wan Yi, Mukhri Hamdan, Giribabu Nelli

    pp. 1195–1205 · DOI: 10.5530/ijpi.20250416 · 2025

    Background Male infertility is associated with vitamin D deficiency, and much evidence suggests ways to correct this deficiency to restore fertility. Vitamin D supplementation in men significantly improved fertility and …

  6. Article

    Gobu, Emmanuel, Daniel Sundar Singh, Prakashraj Elumalai, Roshan Nawaz Ayas, Solai Ganesh Subburaj

    pp. 1206–1213 · DOI: 10.5530/ijpi.20250299 · 2025

    Background Cardiovascular diseases are increasingly becoming a major cause of morbidity and mortality around the world. About half of the deaths due to non-communicable diseases are attributed to some form of cardiovascu…

  7. Article

    Rajendran, Sudesh Raj, Tejas, Jayakumar, Sneha, Reethi

    pp. 1214–1226 · DOI: 10.5530/ijpi.20250211 · 2025

    Background Ashwagandha (Withania somnifera), traditionally valued for enhancing stress resilience, is known for its neuroprotective and antioxidant effects. This study explores the Orgaheal™ Ashwagandha with Valerian Roo…

  8. Article

    Monish Mukul Das, Sayan Chakraborty, Avijit Mondal, Tapas Guha

    pp. 1227–1234 · DOI: 10.5530/ijpi.20250261 · 2025

    Background Staphylococcus aureus is a gram-positive pathogen which contributes community-associated and nosocomial serious diseases and it has become resistant to various antimicrobials. Owing to rapid advent and continu…

  9. Article

    Rashed Mohammed Alghamdi

    pp. 1235–1248 · DOI: 10.5530/ijpi.20250268 · 2025

    Background Non-Small Cell Lung Cancer (NSCLC) epitomizes 85% of lung cancer cases with poor survival rates. Understanding molecular mechanisms through gene expression analysis is important for developing real treatments.…

  10. Article

    Belum Jyoshna, Vadlavari Pavan Chandu, Valmiki Uday Sai, Gaddam Vamsidhar Reddy, Bandi Sai Supraja, Caleerappa Ravi Shankar, Akkiraju Sudheer

    pp. 1249–1253 · DOI: 10.5530/ijpi.20250300 · 2025

    Background According to WHO Drug Utilization research, it is defined as "the marketing, distribution, prescription, and use of drugs in a society, with special emphasis on the resulting medical, social, and economic cons…

  11. Article

    Sandeep Subhash Sagare, Srinivas Prasad Buduru, Kavita Sutagatti, Zeba Mulla

    pp. 1254–1260 · DOI: 10.5530/ijpi.20250306 · 2025

    Background/Purpose Anemia poses a significant public health challenge, particularly in developing nations. Indian government has initiated several programs aimed at reducing the prevalence of anemia, such as providing ir…

  12. Article

    Daniel Sundar Singh, Anand Pithadia, Lavanya

    pp. 1268–1273 · DOI: 10.5530/ijpi.20250317 · 2025

    Background Cardiovascular disease is the major cause of morbidity and mortality in individuals with T2DM. Although many promising cardiac markers have been identified, a single Natriuretic peptide biomarker is unlikely t…

  13. Article

    Pratik Naveenkumar Magadum, Shivamantesh Ashok Kittur, Shashidhar Mallikarjun Javali, Gahana Lokeshwar, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, B J Abhishek, Om Prakash Bhallaram Choudary, Aasiya Nadaf, Sachin Basavaraj, Srajana Shetty, Rakshita Paladi

    pp. 1274–1280 · DOI: 10.5530/ijpi.20250320 · 2025

    Background: Chronic Kidney Disease (CKD) is a global health issue characterized by a gradual decline in kidney function, often leading to reduced health-related quality of life (HRQoL). Despite CKD affecting 8-16% of the…

  14. Article

    Akshata Gore, Arfa Anwar Sayed, Shamita Shyam Sail, Ramish Khan, Agadi Hiremath Viswanatha Swamy, Sanatkumar Bharmu Nyamagoud

    pp. 1281–1287 · DOI: 10.5530/ijpi.20250325 · 2025

    Background Medical devices are used vitally in the healthcare system. Since India is a developing country, it didn’t have a valid outline to screen and notice the adverse events occurred using medical devices. Hence, mat…

  15. Article

    Arfa Anwar Sayed, Akshata Gore, Shamita Shyam Sail, Ramish Khan, Agadi Hiremath Viswanatha Swamy, Sanatkumar Bharmu Nyamagoud

    pp. 1288–1297 · DOI: 10.5530/ijpi.20250326 · 2025

    Background The Materiovigilance Programme of India (MvPI) was launched on 6th July 2015 by the (DCGI) at the Indian Pharmacopoeia Commission, to ensure the safety and effectiveness of medical devices. With the increasing…

  16. Article

    Om Prakash Bhallaram Choudary, Aasiya Nadaf, Pratiksha Bajarang Bhandare, Agadi Hiremath Viswanatha Swamy, Sanatkumar Bharamu Nyamagoud, Abhishek B J, Pratik Naveenkumar Magadum, Shivamantesh Ashok Kittur, Chandrashekar Mallikarjun Patil, Vinod Ashok Koujalagi

    pp. 1298–1303 · DOI: 10.5530/ijpi.20250333 · 2025

    Background Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder in young women, marked by hormonal imbalances, insulin resistance, and elevated androgens. Each of these factors causes medical conditions such a…

  17. Article

    Akshata Manjunath Purantar, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Bibi Khuteja Jangliwale, Kaushal Kumar, Rakshita T P

    pp. 1304–1310 · DOI: 10.5530/ijpi.20250334 · 2025

    Background Older adults are at a higher risk of experiencing drug-drug interactions due to their tendency to use several medications simultaneously, which may include prescription medications, over-the-counter products a…

  18. Article

    Yogita Shinde, Gitanjali Deokar

    pp. 1311–1319 · DOI: 10.5530/ijpi.20250345 · 2025

    Introduction The demand for natural excipients in pharmaceuticals has driven interest in plant-based materials. Lepidium sativum seed mucilage, a polysaccharide-rich and biocompatible compound, shows promise as a tablet …

  19. Article

    Anchal Kushwaha, Kandasamy Nagarajan, Richa Goel, Garima Kapoor, Snigdha Bhardwaj, Pankaj Bhatt

    pp. 1320–1331 · DOI: 10.5530/ijpi.20251665 · 2025

    Background Olmesartan (OLM) is a drug used to treat hypertension, or elevated blood pressure. Controlling high blood pressure lowers the chance of further strokes, renal problems and heart attacks. Materials and Methods …

  20. Article

    Kadambari Solankure, Vinod Gurav, Usharani Sanu, Nayana Bhagat, Eksheka Mall

    pp. 1332–1339 · DOI: 10.5530/ijpi.20250294 · 2025

    Background Prakriti is a unique concept, which exceptionally finds its presence in Ayurveda. It is the unique psychosomatic constitution of an individual, constituted on the basis of the innate qualities of the matruja b…