Volume 16, Issue 1

Oyitabu Ifunanya Mercy, Vemula Kusum Devi, Vijaya Gopalachar Joshi, Gagana Dhanalakshma Nayaka, Urmila Gurupadhaya Hiremath, Malviya Nidhi, Priyanka Nandibasappa, Rama Bukka, Rama Radhakrishna Nargund, Shravan Laxmivenkatesh Nargund, Shachindra Laxmivenkatesh Nargund

pp. 1–11 · DOI: 10.5530/ijpi.20260415 · 2025

Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons and the presence of Lewy body pathology. Its prevalence increases with age, affecting approxi…

Lakshmi Prasanthi Nori, Chintakrindi Parvesh, Akshaya Ratna Kireeti, Jyothika Chittala, Lavanya Chintalapati, Kudeti Himaja Kasturi, Kalidindi Venkateswara Raju

pp. 12–22 · DOI: 10.5530/ijpi.20260001 · 2025

The integration of nanomedicine with personalized medicine represents a transformative paradigm in healthcare, significantly enhancing the diagnosis, treatment, and prevention of diseases. However, the regulatory framewo…

Sandeep Talari, Vivek Reddy Murthannagari, Gundavarapu Kanaka Phani Kumar, Gowthamarajan Kuppusamy, Srikanth Jupudi

pp. 23–29 · DOI: 10.5530/ijpi.20260314 · 2025

In healthcare, adaptive AI and machine learning offer continuous performance improvement through patient data updates, but traditional regulation methods are slow and cumbersome. The USFDA and EMEA propose a paradigm shi…

Jehath Syed, Christy Thomas, Bavneet Kaur, Prathibha Pereira, Tejaswini Chittanahalli Jayaram, Krishna Undela, Ramesh Madhan, Pramod Kumar Teggina Math, Vikarm Patil, Shilpa Avarebeel, Kshama Ramesh, Sri Harsha Chalasani

pp. 30–42 · DOI: 10.5530/ijpi.20260506 · 2025

Drug-Related Problems (DRPs) are common among hospitalized older adult patients and can lead longer hospital stays, worsening clinical conditions, increased healthcare costs, and even death. Artificial Intelligence (AI)-…

Vishal Sachan, Tanveer Naved, Ajay Sachan, Yamini Kohli

pp. 43–50 · DOI: 10.5530/ijpi.20260343 · 2025

Background The criminal offences under the Drugs and Cosmetics Act, 1940 (DCA) directly affect the life of people in India. As per statute, it is obligatory for Drugs Inspector to conduct investigation and execute furthe…

Soiba Siddiqui, Madhan Ramesh, Prashanth Sathya Narayana

pp. 51–57 · DOI: 10.5530/ijpi.20260414 · 2025

The integration of digital surveillance and Artificial Intelligence (AI) technology constitutes a significant shift in Adverse Event Following Immunization (AEFI) monitoring. This review explores the artificial intellige…

Satya Obbalareddy, Anubhav Dubey, Mamta Kumari, Chandan Mukherjee, Sanyogita Shahi, Sayantan Dutta

pp. 58–65 · DOI: 10.5530/ijpi.20260462 · 2025

Nearly 70% of the population will be infected with Human Papillomavirus (HPV) at some point in their lives; in India, 27,526 women are diagnosed with the virus each year, and 79,906 lose their lives to it. Research has l…

Ruchi Tiwari, Priyanka Shukla, Gaurav Tiwari, Mahesh Kumar Posa, Mallikarjun Mugli, Anurag Mishra

pp. 66–76 · DOI: 10.5530/ijpi.20260447 · 2025

A biopolymer is a naturally derived polymer, obtained from living organisms like plants, animals and various microorganism. The biopolymer is made up of various monomer units which are linked together with each other thr…

Paramita Ganguly, Puja Saha, Sourav Khawas, Sandip Chatterjee, Arvind Kumar Patel, Prangyan Paramita Pati

pp. 77–88 · DOI: 10.5530/ijpi.20260499 · 2025

Microneedles, first introduced in 1976, address these limitations by creating tiny, non-invasive channels that enhance drug penetration through the skin. Transdermal Drug Delivery (TDD) is a less intrusive approach that …

Mamatha Gavisiddaiah, Kenganora Mruthunjaya, Santhepete Nanjundaiah Manjula

pp. 89–97 · DOI: 10.5530/ijpi.20260338 · 2025

Alzheimer's Disease (AD), characterised by cognitive impairment and memory loss, is primarily caused by the deterioration of the central nervous system, which is a vital component of the human body. Amyloid-beta plaque b…

Kirtimaya Mishra, Asra Jabeen, Sarojini Nayak, Ritupriya Mohanty, Debasis Patra, Diptimayee Jena

pp. 98–104 · DOI: 10.5530/ijpi.20260472 · 2025

The sustainable substitute for conventional nanomaterials, Plant-Derived Nanoparticles (PDNPs), employ green synthesis techniques to reduce their negative effects on the environment while increasing their medicinal effec…

N Amitha, DS Sandeep, P Rajanikant, MP Gowrav, S Kathirvel, HK Pradeep, MR Jeyaprakash

pp. 105–110 · DOI: 10.5530/ijpi.20260359 · 2025

Cubosomes are self-assembled nanostructures that exhibit a bicontinuous cubic phase. These nanoparticles can incorporate many drugs, including amphiphilic, hydrophilic, and lipophilic substances. The structure of cubosom…

Chinna Reddy Palem, Ravinder Rendla, Vamshi Krishna Lekkala, Neha Andhi, Nishant Kumar Nagamalli, Deepthi Battula, Sridhar Gumudevelli

pp. 111–122 · DOI: 10.5530/ijpi.20260433 · 2025

Oral transmucosal drug delivery systems represent an innovative approach for the administration of therapeutic agents through the mucosal membranes, such as sublingual and buccal membranes in the mouth, offering advantag…

S K Kavitha, Mohammad Ali

pp. 123–132 · DOI: 10.5530/ijpi.20260573 · 2025

Background To assess in vivo antidepressant of Ethanolic extract of Albizzia lebbeck (L.) own their family Fabaceae the plant's primary constituents Triterpenes, glycosides, saponins, flavonoids, and indole alkaloids are…

Payal Shah, Gaurang Shah

pp. 133–142 · DOI: 10.5530/ijpi.20260444 · 2025

Background Reactive oxygen species (ROS), produced by different enzymes, play a role in oxidative stress, which is linked to the development of many diseases. The NADPH oxidase (NOX) enzyme family serves as a primary sou…

Anushree Shrikant Deshpande, Madiwalayya Shivakantayya Ganachari

pp. 143–154 · DOI: 10.5530/ijpi.20260494 · 2025

Background Diabetes Mellitus (DM) is a serious worldwide health challenge, currently affecting over 425 million people globally. India bears a significant burden, with approximately 74 million diagnosed cases as of 2021.…

Vinod Ashokdas Bairagi, Deepak Balasaheb Somavanshi, Yogesh Suresh Ahire, Jayashri Sanjay Nikam, Swapnil Bandu Jadhav, Mohammed Saad Abdul Hameed, Chandrashekhar Dinkar Patil, Amol Mohan Shirode, Mohammad Ikrama

pp. 155–166 · DOI: 10.5530/ijpi.20260003 · 2025

Background The discovery of efficacious anti-stress therapies is imperative, as chronic stress plays a substantial role in the development of numerous physical and mental health issues. Materials and Methods The present …

Kishori Prasanna Sutar, Sunil Satyappa Jalalpure

pp. 167–173 · DOI: 10.5530/ijpi.20260513 · 2025

Background The proposed study focuses on developing and validating a sensitive and simple UV-spectroscopic technique for apremilast quantification in bulk drug, commercial tablet, cubosomes and transferosomes. Materials …

Pruthviraj Vijay Kute, Rohit Jaysing Bhor, Mahesh Hari Kolhe, Harshada Shubhash Bhosale, Pornima Ramdas Tambe, Mayuri Rajesh Bhoknal, Pratibha Shankar Jadhav, Swapnali Baban Avhad, Mayuri Girish Dharam, Ajay Sanjay Mule

pp. 174–183 · DOI: 10.5530/ijpi.20260361 · 2025

Background The computational study of benzimidazole derivatives is the main topic of this article. All compounds' cytotoxicity against inflammation was assessed, and the outcomes showed that several of them had strong in…

Suresh Kumar Thirumoorthi, Rama Prabha Mani

pp. 184–192 · DOI: 10.5530/ijpi.20260303 · 2025

Objectives The study was aimed to investigate the presences of bioactive components by Debregeasia longifolia through Gas Chromatography-Mass Spectrometry (GC-MS) analysis and evaluate its in vitro free radical scavengin…